Micronutrients/miRs/ATP networking in mitochondria: Clinical intervention with ferroptosis, cuproptosis, and calcium burden

SP Panda, A Kesharwani - Mitochondrion, 2023 - Elsevier
The mitochondrial electron transport chain (mtETC) requires mainly coenzyme Q10
(CoQ10), copper (Cu 2+), calcium (Ca 2+), and iron (Fe 2+) ions for efficient ATP production …

Optimal serum ferritin level range: Iron status measure and inflammatory biomarker

RG DePalma, VW Hayes, TJ O'Leary - Metallomics, 2021 - academic.oup.com
This report provides perspectives concerning dual roles of serum ferritin as a measure of
both iron status and inflammation. We suggest benefits of a lower range of serum ferritin as …

Research progress of ferroptosis regulatory network and bone remodeling in osteoporosis

C Yan, J Zhang, F An, J Wang, Y Shi, L Yuan… - Frontiers in Public …, 2022 - frontiersin.org
Ferroptosis was induced the programmed cell death with iron overload Fenton reaction.
Currently, ferroptosis has not been studied thoroughly. Existing studies have confirmed that …

Iron metabolism in the tumor microenvironment: contributions of innate immune cells

W Liang, N Ferrara - Frontiers in Immunology, 2021 - frontiersin.org
Cells of the innate immune system are a major component of the tumor microenvironment.
They play complex and multifaceted roles in the regulation of cancer initiation, growth …

Explaining kinetic trends of inner-sphere transition-metal-ion redox reactions on metal electrodes

H Agarwal, J Florian, D Pert, BR Goldsmith… - ACS Catalysis, 2023 - ACS Publications
Transition-metal ions regularly undergo charge transfer (CT) by directly interacting with
electrodes, and this CT governs the performance of devices for numerous applications like …

A diet of oxidative stress–adapted bacteria improves stress resistance and lifespan in C. elegans via p38-MAPK

A Bhat, RL Cox, BG Hendrickson, NK Das… - Science …, 2024 - science.org
Organisms across taxa face stresses including variable temperature, redox imbalance, and
xenobiotics. Successfully responding to stress and restoring homeostasis are crucial for …

[HTML][HTML] The mitochondrial regulation in ferroptosis signaling pathway and its potential strategies for cancer

K Sun, Y Zhi, W Ren, S Li, X Zhou, L Gao… - Biomedicine & …, 2023 - Elsevier
Ferroptosis is an iron-dependent regulated cell death, mainly manifested by the production
of reactive oxygen species and accumulation of lipid peroxides. It is distinct from other forms …

Decreasing brain iron in multiple sclerosis: The difference between concentration and content in iron MRI

F Schweser, J Hagemeier, MG Dwyer… - Human brain …, 2021 - Wiley Online Library
Increased brain iron concentration is often reported concurrently with disease development
in multiple sclerosis (MS) and other neurodegenerative diseases. However, it is unclear …

Ferroptosis meets cell–cell contacts

C Dietrich, TG Hofmann - Cells, 2021 - mdpi.com
Ferroptosis is a regulated form of cell death characterized by iron dependency and
increased lipid peroxidation. Initially assumed to be selectively induced in tumour cells …

The IRONy in Athletic Performance

W Kardasis, ER Naquin, R Garg, T Arun, JS Gopianand… - Nutrients, 2023 - mdpi.com
Iron is an essential micronutrient for athletes, intricately linked to their performance, by
regulating cellular respiration and metabolism. Impaired iron levels in the body can …