Background Iron is essential to brain function, and iron deficiency during youth may
adversely impact neurodevelopment. Understanding the developmental time course of iron …

Iron (Fe) is an essential element that plays a fundamental role in a wide range of cellular
functions, including cellular proliferation, DNA synthesis, as well as DNA damage and …

Iron is an essential trace element in the metabolism of almost all living organisms. Iron
overload can disrupt bone homeostasis by significant inhibition of osteogenic differentiation …

Cytochrome P450 (CYP) 1B1 belongs to the superfamily of heme-containing
monooxygenases. Unlike other CYP enzymes, which are highly expressed in the liver …

Diabetic cardiomyopathy (DC) is a serious heart disease caused by diabetes. It is unrelated
to hypertension and coronary artery disease and can lead to heart insufficiency, heart failure …

Striatal development is crucial for later motor, cognitive, and reward behavior, but age-
related change in striatal physiology during the neonatal period remains understudied. An …

Background: iron and calcium dysmetabolism, with hyperferritinemia, hypoferremia,
hypocalcemia and anemia have been documented in the majority of COVID-19 patients at …

Coronavirus disease-19 (COVID-19), caused by severe acute respiratory syndrome
coronavirus type 2 (SARS-CoV-2), is associated with the persistence of pre-existing or the …

Iron metabolism plays a crucial role in the development and progression of hepatocellular
carcinoma (HCC), the most common type of primary liver cancer. Iron is an essential …

Germline-mutation in BRCA1 tumor suppressor gene is an established risk for
carcinogenesis not only in females but also in males. Deficiency in the repair of DNA double …