Type 2 diabetes (T2DM) and its complications constitute a major worldwide public health
problem, with high rates of morbidity and mortality. Biomarkers for predicting the occurrence …

A direct and an indirect relationship between paraoxonase 1 (PON1) and atherosclerosis
exists. Given PON1's physical location within high‐density lipoprotein (HDL) particles and its …

Cardiovascular disease is one of the leading causes of morbidity and mortality worldwide,
with increasing incidence. A cornerstone of cardiovascular disease prevention is lifestyle …

Abstract Type 2 Diabetes Mellitus (T2DM) is a chronic metabolic disease with symptoms that
go beyond the domain of glucose metabolism. In fact, research has shown that T2DM is …

Proteinopathies are characterized by aging related accumulation of misfolded protein
aggregates. Irreversible covalent modifications of aging proteins may significantly affect the …

We carried out this meta‐analysis to explore the influence of paraoxonase 1 activity on the
susceptibility of diabetes mellitus (DM), diabetic macroangiopathy and diabetic …

Background The aim of the study was to investigate the association of paraoxonase 1
(PON1) polymorphism, PON1/arylesterase (ARE) activity and oxidative stress index (OSI) in …

Abstract Mutations in the Paraoxonase 1 (Pon1) gene underlie aging, cardiovascular
disease, and impairments of the nervous and gastrointestinal systems and are linked to the …

Objective: To examine concentration of Paraoxonase 1 enzymes across both Sudanese
patients suffering from Type-I and Type-II diabetes. Methods: This was a cross-sectional …

Background: Paraoxonase (PON) is a family of calcium-dependent hydrolases, which is
related to many diseases. Elucidation of PON physiological roles, active center and all …