Estrogen has been postulated as a contributor for lung cancer development and
progression. We reviewed the current knowledge about the expression and prognostic …

Deregulation of tumor cell metabolism is widely recognized as a “hallmark of cancer.” Many
of the selective pressures encountered by tumor cells, such as exposure to anticancer …

Non-genetic mechanisms have recently emerged as important drivers of cancer therapy
failure, where some cancer cells can enter a reversible drug-tolerant persister state in …

Lung cancer (LC) is the leading cause of cancer death in men worldwide and has
significantly increased in women. Differences in non-small cell lung cancer (NSCLC) …

Objectives Dichloroacetate (DCA) is a highly bioavailable small molecule that inhibits
pyruvate dehydrogenase kinase, promoting glucose oxidation and reversing the glycolytic …

It is becoming increasingly clear that steroid hormones are involved in the biology of many
organs outside the reproductive system. Evidence has been accumulating since the mid …

High levels of the estrogen receptor β (ERβ) predict poor prognosis following platinum-
containing adjuvant chemotherapies in patients with non-small cell lung cancer (NSCLC) …

Lung cancer incidence and mortality have significantly increased in women worldwide. Lung
adenocarcinoma is the most common form of lung cancer globally. This type of lung cancer …

Purpose: Breast cancer (BC) and lung cancer are the most two common cancers with
highest morbidity and mortality for women. With prolonged survival, there comes the …

Estrogen has been postulated to contribute to the development and progression of lung
cancer. We examined the epidemiologic evidence, explored the characteristics of estrogen …