Extensive research over the past half a century indicates that reactive oxygen species (ROS)
play an important role in cancer. Although low levels of ROS can be beneficial, excessive …

Angiogenesis is the process of blood vessel growth. The angiogenic switch consists of new
blood vessel formation that, in carcinogenesis, can lead to the transition from a harmless …

The NADPH oxidase (NOX) family of enzymes produces ROS as their sole function and is
becoming recognized as key modulators of signal transduction pathways with a …

Current studies on tumor progression focus on the roles of cytokines in the tumor
microenvironment (TME), and recent research shows that transforming growth factor‐β1 …

Reactive oxygen species (ROS) represent reactive products belonging to the partial
reduction of oxygen. It has been reported that ROS are involved in different signaling …

The formation of reactive oxygen species (ROS) by the myeloid cell NADPH oxidase NOX2
is critical for the destruction of engulfed microorganisms. However, recent studies imply that …

Nicotinamide adenine dinucleotide phosphate (NADPH) oxidase 4 (NOX4) is one of the
seven isoforms of NOX family, which is upregulated in pancreatic cancer cell, mouse model …

Abstract NADPH oxidase 4 (NOX4), a major source of reactive oxygen species (ROS)
production, has been increasingly reported to be involved in tumorigenesis and/or tumor …

Glioma cells use intermediate levels of reactive oxygen species (ROS) and reactive nitrogen
species (RNS) for growth and invasion, and suppressing these reactive molecules thus may …

Glioblastoma is an aggressive tumor and is associated with a dismal prognosis. The
availability of few active treatments as well as the inexorable recurrence after surgery are …