Ecology of aspergillosis: insights into the pathogenic potency of Aspergillus fumigatus and some other Aspergillus species

C Paulussen, JE Hallsworth… - Microbial …, 2017 - Wiley Online Library
Fungi of the genus Aspergillus are widespread in the environment. Some Aspergillus
species, most commonly Aspergillus fumigatus, may lead to a variety of allergic reactions …

Pathogenesis of Aspergillus fumigatus in Invasive Aspergillosis

TRT Dagenais, NP Keller - Clinical microbiology reviews, 2009 - Am Soc Microbiol
Aspergillus species are globally ubiquitous saprophytes found in a variety of ecological
niches. Almost 200 species of aspergilli have been identified, less than 20 of which are …

[HTML][HTML] Aspergillus Galactosaminogalactan Mediates Adherence to Host Constituents and Conceals Hyphal β-Glucan from the Immune System

FN Gravelat, A Beauvais, H Liu, MJ Lee… - PLoS …, 2013 - journals.plos.org
Aspergillus fumigatus is the most common cause of invasive mold disease in humans. The
mechanisms underlying the adherence of this mold to host cells and macromolecules have …

[HTML][HTML] Als3 is a Candida albicans invasin that binds to cadherins and induces endocytosis by host cells

QT Phan, CL Myers, Y Fu, DC Sheppard… - PLoS …, 2007 - journals.plos.org
Candida albicans is the most common cause of hematogenously disseminated and
oropharyngeal candidiasis. Both of these diseases are characterized by fungal invasion of …

[HTML][HTML] The spectrum of pulmonary aspergillosis

A Kanj, N Abdallah, AO Soubani - Respiratory medicine, 2018 - Elsevier
Notable progress has been made in the past years in the classification, diagnosis and
treatment of pulmonary aspergillosis. New criteria were proposed by the Working Group of …

Pharmacokinetic/pharmacodynamic profile of voriconazole

U Theuretzbacher, F Ihle, H Derendorf - Clinical pharmacokinetics, 2006 - Springer
Voriconazole is the first available second-generation triazole with potent activity against a
broad spectrum of clinically significant fungal pathogens, including Aspergillus, Candida …

[HTML][HTML] Fungal invasion of normally non-phagocytic host cells

SG Filler, DC Sheppard - PLoS pathogens, 2006 - journals.plos.org
Many fungi that cause invasive disease invade host epithelial cells during mucosal and
respiratory infection, and subsequently invade endothelial cells during hematogenous …

Hyphal growth in human fungal pathogens and its role in virulence

A Brand - International journal of microbiology, 2012 - Wiley Online Library
Most of the fungal species that infect humans can grow in more than one morphological form
but only a subset of pathogens produce filamentous hyphae during the infection process …

[PDF][PDF] Genes and molecules involved in Aspergillus fumigatus virulence

A Rementeria, N López-Molina, A Ludwig… - Rev Iberoam …, 2005 - reviberoammicol.com
Aspergillus fumigatus causes a wide range of diseases that include mycotoxicosis, allergic
reactions and systemic diseases (invasive aspergillosis) with high mortality rates …

[HTML][HTML] The pH-Responsive PacC Transcription Factor of Aspergillus fumigatus Governs Epithelial Entry and Tissue Invasion during Pulmonary Aspergillosis

M Bertuzzi, M Schrettl, L Alcazar-Fuoli, TC Cairns… - PLoS …, 2014 - journals.plos.org
Destruction of the pulmonary epithelium is a major feature of lung diseases caused by the
mould pathogen Aspergillus fumigatus. Although it is widely postulated that tissue invasion …