Ten years after Fire and Melo's Nobel Prize for discovery of gene silencing by double-
stranded RNA, a remarkable progress was achieved in RNA interference (RNAi). Changes …

Glaucoma is one of the leading causes of irreversible blindness. Progression is halted with a
reduction in intraocular pressure (IOP), which is most often achieved with eye drops. A major …

Predicting the incidence of complex chronic conditions such as heart failure is challenging.
Deep learning models applied to rich electronic health records may improve prediction but …

A fixed combination of bimatoprost/timolol eye drop solution is used to manage the elevated
intra-ocular pressure in glaucoma patients, including individuals whose condition is poorly …

Stimuli-responsive drug delivery systems have attracted widespread attention in recent
years since they can control drug release in a spatiotemporal manner and can achieve …

Glaucoma therapy-related ocular surface disease (OSD) is a serious pathology with a broad
spectrum of insidious clinical presentations and complex pathogenesis that undermines …

Optimal vision remains one of the most essential elements of the sensory system
continuously threatened by many ocular pathologies. Various pharmacological agents …

The increment in ocular drug bioavailability after topical administration is one of the main
challenges in pharmaceutical technology. For several years, different strategies based on …

Glaucoma is the leading cause of irreversible blindness worldwide. As a chronic disease,
glaucoma presents a significant burden to the individual, health‐care provider and the …

Polypharmacy is a common observation among older adults secondary to their complex
medical needs requiring management with 1 or more medications. The use of numerous …