As an essential branch of targeted drug delivery, oral targeted delivery is attracting growing
attention in recent years. In addition to site-specific delivery for the treatment of locoregional …

The amorphous form of a drug can greatly improve the solubility and rates of dissolution for
enhancing oral bioavailability. However, amorphous drugs tend to crystallize thus negating …

Amorphous solid dispersion (ASD) has been widely used to enhance the oral bioavailability
of water-insoluble drugs for oral delivery because of its advantages of enhancing solubility …

Docetaxel (DTX) has become one of the most important cytotoxic drugs to treat cancer;
nevertheless, its poor hydrophilicity and non-specific distribution of DTX lead to detrimental …

Gemcitabine (GEM) is a non-selective chemotherapeutic agent used in the treatment of
pancreatic cancer. Its antitumor efficacy is limited by a short plasma half-life and severe …

Förster resonance energy transfer (FRET) probes are a promising tool for studying
numerous biochemical processes. In this paper, we show the application of the FRET …

Tranexamic acid (TXA) is an anti-fibrinolysis agent widely used in postoperative blood loss
management. As a highly water-soluble drug, TXA is suffering from rapid clearance from the …

The complex environment in blood circulation has a tremendous destabilizing effect on the
micelles structure, which is a vital issue to be addressed in micelles design and application …

There are several well-known methods for determining enzyme catalytic activity, including
spectral techniques and electrochemical approaches. However, at present, there is no …