[HTML][HTML] Jet injectors: Perspectives for small volume delivery with lasers
J Schoppink, DF Rivas - Advanced drug delivery reviews, 2022 - Elsevier
Needle-free jet injectors have been proposed as an alternative to injections with hypodermic
needles. Currently, a handful of commercial needle-free jet injectors already exist. However …
needles. Currently, a handful of commercial needle-free jet injectors already exist. However …
[HTML][HTML] The delivery of mRNA vaccines for therapeutics
Nitika, J Wei, AM Hui - Life, 2022 - mdpi.com
mRNA vaccines have been revolutionary in combating the COVID-19 pandemic in the past
two years. They have also become a versatile tool for the prevention of infectious diseases …
two years. They have also become a versatile tool for the prevention of infectious diseases …
[HTML][HTML] Iontophoresis-driven microneedle patch for the active transdermal delivery of vaccine macromolecules
Y Zheng, R Ye, X Gong, J Yang, B Liu, Y Xu… - Microsystems & …, 2023 - nature.com
COVID-19 has seriously threatened public health, and transdermal vaccination is an
effective way to prevent pathogen infection. Microneedles (MNs) can damage the stratum …
effective way to prevent pathogen infection. Microneedles (MNs) can damage the stratum …
[HTML][HTML] Microarray patches enable the development of skin-targeted vaccines against COVID-19
E Korkmaz, SC Balmert, TL Sumpter, CD Carey… - Advanced drug delivery …, 2021 - Elsevier
The COVID-19 pandemic is a serious threat to global health and the global economy. The
ongoing race to develop a safe and efficacious vaccine to prevent infection by SARS-CoV-2 …
ongoing race to develop a safe and efficacious vaccine to prevent infection by SARS-CoV-2 …
Devices for drug delivery in the gastrointestinal tract: A review of systems physically interacting with the mucosa for enhanced delivery
The delivery of macromolecules via the gastrointestinal (GI) tract remains a significant
challenge. A variety of technologies using physical modes of drug delivery have been …
challenge. A variety of technologies using physical modes of drug delivery have been …
[HTML][HTML] The right Timing, right combination, right sequence, and right delivery for Cancer immunotherapy
Cancer immunotherapy (CI) represented by immune checkpoint inhibitors (ICIs) presents a
new paradigm for cancer treatment. However, the types of cancer that attain a therapeutic …
new paradigm for cancer treatment. However, the types of cancer that attain a therapeutic …
[HTML][HTML] Clinical perspective on topical vaccination strategies
Vaccination is one of the most successful measures in modern medicine to combat
diseases, especially infectious diseases, and saves millions of lives every year. Vaccine …
diseases, especially infectious diseases, and saves millions of lives every year. Vaccine …
DNA-Based Nonviral Gene Therapy─ Challenging but Promising
X Guan, Y Pei, J Song - Molecular Pharmaceutics, 2024 - ACS Publications
Over the past decades, significant progress has been made in utilizing nucleic acids,
including DNA and RNA molecules, for therapeutic purposes. For DNA molecules, although …
including DNA and RNA molecules, for therapeutic purposes. For DNA molecules, although …
[HTML][HTML] Mapping the mechanical and immunological profiles of polymeric microneedles to enable vaccine and immunotherapy applications
Biomaterials hold great promise for vaccines and immunotherapy. One emerging
biomaterials technology is microneedle (MNs) delivery. MNs are arrays of micrometer-sized …
biomaterials technology is microneedle (MNs) delivery. MNs are arrays of micrometer-sized …
The use of electroporation to deliver DNA-based vaccines
DN Kisakov, IM Belyakov, LA Kisakova… - Expert Review of …, 2024 - Taylor & Francis
Introduction Nucleic acids represent a promising platform for creating vaccines. One
disadvantage of this approach is its relatively low immunogenicity. Electroporation (EP) is an …
disadvantage of this approach is its relatively low immunogenicity. Electroporation (EP) is an …