A review of pulmonary toxicity of electronic cigarettes in the context of smoking: a focus on inflammation

PG Shields, M Berman, TM Brasky… - … Biomarkers & Prevention, 2017 - AACR
The use of electronic cigarettes (e-cigs) is increasing rapidly, but their effects on lung toxicity
are largely unknown. Smoking is a well-established cause of lung cancer and respiratory …

An epidemiological introduction to human metabolomic investigations

AD Joshi, A Rahnavard, P Kachroo, KM Mendez… - Trends in Endocrinology …, 2023 - cell.com
Metabolomics holds great promise for uncovering insights around biological processes
impacting disease in human epidemiological studies. Metabolites can be measured across …

Circulating pro-and anti-inflammatory metabolites and its potential role in rheumatoid arthritis pathogenesis

R Coras, JD Murillo-Saich, M Guma - Cells, 2020 - mdpi.com
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease that affects synovial
joints, leading to inflammation, joint destruction, loss of function, and disability. Although …

[HTML][HTML] Maternal serum metabolome and traffic-related air pollution exposure in pregnancy

Q Yan, Z Liew, K Uppal, X Cui, C Ling, JE Heck… - Environment …, 2019 - Elsevier
Background Maternal exposure to traffic-related air pollution during pregnancy has been
shown to increase the risk of adverse birth outcomes and neurodevelopmental disorders. By …

Pathophysiology and genomics of bronchiectasis

L Perea, R Faner, JD Chalmers… - European Respiratory …, 2024 - err.ersjournals.com
Bronchiectasis is a complex and heterogeneous inflammatory chronic respiratory disease
with an unknown cause in around 30–40% of patients. The presence of airway infection …

Omics and the search for blood biomarkers in chronic obstructive pulmonary disease. Insights from COPDGene

EA Regan, CP Hersh, PJ Castaldi… - American journal of …, 2019 - atsjournals.org
There is an unmet need for blood biomarkers in diagnosis and prognosis of chronic
obstructive pulmonary disease (COPD). The search for these biomarkers has been …

High-resolution metabolomics of exposure to tobacco smoke during pregnancy and adverse birth outcomes in the Atlanta African American maternal-child cohort

Y Tan, DB Barr, PB Ryan, V Fedirko, JA Sarnat… - Environmental …, 2022 - Elsevier
Exposure to tobacco smoke during pregnancy has been associated with a series of adverse
reproductive outcomes; however, the underlying molecular mechanisms are not well …

The impact of ambient air pollution on the human blood metabolome

JJ Vlaanderen, NA Janssen, G Hoek… - Environmental …, 2017 - Elsevier
Background Biological perturbations caused by air pollution might be reflected in the
compounds present in blood originating from air pollutants and endogenous metabolites …

[HTML][HTML] Investigations in the possibility of early detection of colorectal cancer by gas chromatography/triple-quadrupole mass spectrometry

S Nishiumi, T Kobayashi, S Kawana, Y Unno, T Sakai… - Oncotarget, 2017 - ncbi.nlm.nih.gov
In developed countries, the number of patients with colorectal cancer has been increasing,
and colorectal cancer is one of the most common causes of cancer death. To improve the …

Comparison of collection methods for fecal samples for discovery metabolomics in epidemiologic studies

E Loftfield, E Vogtmann, JN Sampson, SC Moore… - … Biomarkers & Prevention, 2016 - AACR
Background: The gut metabolome may be associated with the incidence and progression of
numerous diseases. The composition of the gut metabolome can be captured by measuring …