Context-specific signaling is a prevalent theme in cancer biology wherein individual
molecules and pathways can have multiple or even opposite effects depending on the tumor …

The mitogen-activated protein kinase (MAPK) pathways are ubiquitous in cellular signaling
and are essential for proper biological functions. Disruptions in this signaling axis can lead …

Background Abnormal activation of the NF-κB pathway is closely related to tumorigenesis
and chemoresistance. Therefore, microRNAs that possess the NF-κB inhibitory activity may …

Background & Aims Oxidative stress-mediated ferroptosis and macrophage-related
inflammation play an important role in various liver diseases. Here, we explored if and how …

Abstract Development and maintenance of leukemia can be partially attributed to alterations
in (anti)-apoptotic gene expression. Genome-wide transcriptome analyses revealed that 89 …

Background TRPV6 is over-expressed and promotes the proliferation and invasion in many
cancers. The association between the expression of TRPV6 and clinical outcome in …

DNA polymerase iota (Pol ι) is an error-prone DNA polymerase involved in translesion DNA
synthesis (TLS) that contributes to the accumulation of DNA mutations. We recently showed …

Objective: This study was intended to identify prognostic biomarkers for lymph node (LN)-
positive locoregional esophageal squamous cell carcinoma (ESCC) patients. Summary of …

Gastric cancer (GC) is the most frequent digestive system malignant tumour and the second
most common cause of cancer death globally. Cancer stem cell (CSC) is a small percentage …

Diffuse large B‐cell lymphoma (DLBCL) is the most common form of lymphoma, and up to
30% DLBCL patients eventually died by using first‐line chemotherapy regimens. Currently …