The COVID-19 pandemic is an emerging threat to global public health. While our current
understanding of COVID-19 pathogenesis is limited, a better understanding will help us …

Severe acute respiratory-syndrome coronavirus-2 (SARS-CoV-2) host cell infection is
mediated by binding to angiotensin-converting enzyme 2 (ACE2). Systemic dysregulation …

Angiotensin‐converting enzyme 2 (ACE2) shares some homology with angiotensin‐
converting enzyme (ACE) but is not inhibited by ACE inhibitors. The main role of ACE2 is the …

In recent years, the focus of interest on the role of the renin-angiotensin system (RAS) in the
pathophysiology of hypertension and organ injury has changed to a major emphasis on the …

Aims Angiotensin converting enzyme (ACE) 2 catalyses the cleavage of angiotensin (Ang) I
to Ang 1‐9 and of Ang II to Ang 1‐7. ACE2 deficiency impairs cardiac contractility and …

Angiotensin-converting enzyme (ACE) is a zinc metalloproteinase and a key regulator of the
renin–angiotensin system (RAS). ACE2 is a newly described enzyme identified in rodents …

Background: Angiotensin converting enzyme (ACE) 2 is a recently identified homologue of
ACE that may counterregulate the actions of angiotensin (Ang) II by facilitating its breakdown …

The renin‐angiotensin system (RAS) is a critical regulator of hypertension, primarily through
the actions of the vasoactive peptide Ang II, which is generated by the action of angiotensin …

Heart failure is a major health problem worldwide. In the United States, it represents the
number one hospital discharge diagnosis among elderly persons each year. It appears most …

The renin-angiotensin system (RAS) has been recognized for many years as critical
pathway for blood pressure control and kidney functions. Although most of the well-known …