Nasopharyngeal carcinoma: an evolving paradigm

KCW Wong, EP Hui, KW Lo, WKJ Lam… - Nature reviews Clinical …, 2021 - nature.com
The past three decades have borne witness to many advances in the understanding of the
molecular biology and treatment of nasopharyngeal carcinoma (NPC), an Epstein–Barr virus …

Salivary gland function, development, and regeneration

AM Chibly, MH Aure, VN Patel… - Physiological …, 2022 - journals.physiology.org
Salivary glands produce and secrete saliva, which is essential for maintaining oral health
and overall health. Understanding both the unique structure and physiological function of …

Radiation-induced salivary gland dysfunction: mechanisms, therapeutics and future directions

KJ Jasmer, KE Gilman, K Muñoz Forti… - Journal of clinical …, 2020 - mdpi.com
Salivary glands sustain collateral damage following radiotherapy (RT) to treat cancers of the
head and neck, leading to complications, including mucositis, xerostomia and …

From static to dynamic: a review on the role of mucus heterogeneity in particle and microbial transport

DD Pednekar, MA Liguori, CNH Marques… - ACS Biomaterials …, 2022 - ACS Publications
Mucus layers (McLs) are on the front line of the human defense system that protect us from
foreign abiotic/biotic particles (eg, airborne virus SARS-CoV-2) and lubricates our organs …

Efficacy of a 1% malic acid spray for xerostomia treatment: a systematic review and meta‐analysis

G Liu, X Qiu, X Tan, R Miao, W Tian, W Jing - Oral Diseases, 2023 - Wiley Online Library
Objectives To assess the efficacy of topical sialogogue spray containing malic acid 1% for
treating xerostomia. Methods We searched PubMed, Cochrane Library, Embase …

[HTML][HTML] Long-term stability of jaw reconstruction with microvascular bone flaps: A prospective longitudinal study

JJ Pu, WS Choi, MCM Wong, S Wu, PH Leung, W Yang… - Oral Oncology, 2024 - Elsevier
Objectives Microvascular bone flap jaw reconstruction has achieved satisfactory clinical
outcomes. However, little is known about the long-term stability of the reconstructed jaw …

World Workshop on Oral Medicine VIII: Development of a core outcome set for dry mouth: a systematic review of outcome domains for xerostomia

P Wiriyakijja, SE Niklander, AR Santos-Silva… - Oral surgery, oral …, 2023 - Elsevier
Objective The purpose of this study was to identify all outcome domains used in clinical
studies of xerostomia, that is, subjective sensation of dry mouth. This study is part of the …

A qualitative analysis of patient's lived experience on their treatment journey with nasopharyngeal carcinoma

JPZ Ng, WYH Lam, EHN Pow, MG Botelho - Journal of Dentistry, 2023 - Elsevier
Objective To explore and analyse the perspective of patients undergoing and recovering
from nasopharyngeal carcinoma (NPC) therapy. Methods Thirty-three NPC patients at …

A prediction model for xerostomia in locoregionally advanced nasopharyngeal carcinoma patients receiving radical radiotherapy

M Li, J Zhang, Y Zha, Y Li, B Hu, S Zheng, J Zhou - BMC Oral Health, 2022 - Springer
Background This study was to evaluate the predictors of xerostomia and Grade 3 xerostomia
in locoregionally advanced nasopharyngeal carcinoma (NPC) patients receiving radical …

Prediction of toxicity outcomes following radiotherapy using deep learning-based models: a systematic review

D Tan, NFM Nasir, HA Manan, N Yahya - Cancer/Radiothérapie, 2023 - Elsevier
Purpose This study aims to perform a comprehensive systematic review of deep learning
(DL) models in predicting RT-induced toxicity. Materials and methods A literature review was …