Noncanonical RNA nucleotidyltransferases (NTases), including poly (A), poly (U)
polymerases (PAPs/PUPs), and C/U-adding enzymes, modify 3′-ends of different …

In eukaryotes, mRNAs with long poly (A) tails are translationally active, whereas
deadenylation of the tails decreases translation and uridylation of the short poly (A) tails …

Most transcription in Trypanosoma brucei is constitutive and polycistronic. Consequently, the
parasite relies on post-transcriptional mechanisms, especially affecting translation initiation …

Sažetak Uridylation is a common widespread 3'-end modification in eukaryotes; however, its
impact on mRNA fate is not clear. The mRNA decay mechanism in S. pombe is quite similar …

Non-coding RNAs (ncRNAs) are powerful regulators of gene expression but medium-sized
(50–300 nts in length) ncRNAs (msRNAs) are barely picked-up precisely by RNA …

Ribonucleases are enzymes which perform the processing and degradation of all types of
RNA, being critical for the tight post-transcriptional regulation of gene expression. Three …

Dis3L2 is a highly conserved 3'-5'exoribonuclease which is mutated in the human
overgrowth disorders Perlman syndrome and Wilms' tumour. Here, we have generated a …

Die Prozessierung und Degradation von RNA sind essentielle Prozesse in den Zellen aller
Domänen des Lebens. Während in Bakterien und Eukaryoten diese Prozesse bereits sehr …

RNA (ribonucleic acid) molecules play vital roles in the eukaryotic cells, not only as
mediators of the flow of genetic information from DNA (deoxyribonucleic acid) to proteins but …

Lin28a inhibits the biogenesis of let-7 miRNAs by triggering the polyuridylation and
degradation of their precursors by terminal uridylyltransferases TUT4/7 and 3′-5 …