Aerosolised drugs are prescribed for use in a range of inhaler devices and systems.
Delivering drugs by inhalation requires a formulation that can be successfully aerosolised …

Asthma is a common inflammatory disease of the lungs. The prevalence of asthma is
increasing worldwide, and the tendency indicates that the number of asthma sufferers will …

Background Systemic glucocorticoids reduce the incidence of bronchopulmonary dysplasia
among extremely preterm infants, but they may compromise brain development. The effects …

This thoroughly revised and expanded reference provides authoritative discussions on the
physiologic, pharmacologic, metabolic, molecular, cellular and physicochemical factors …

Introduction: Respiratory drug delivery is a surprisingly complex process with a number of
physical and biological challenges. Computational fluid dynamics (CFD) is a scientific …

Background Bronchopulmonary dysplasia (BPD), defined as oxygen dependence at 36
weeks postmenstrual age (PMA), remains an important complication of prematurity …

OBJECTIVE. Budesonide is an inhaled steroid with a strong topical effect but with minimal
systemic effects; it has been effectively delivered to animal lungs using surfactant as a …

Bronchopulmonary dysplasia (BPD) remains the most prevalent long-term morbidity of
surviving extremely preterm infants and is associated with significant health care utilization …

Delivery of medications to preterm neonates receiving non-invasive ventilation (NIV)
represents one of the most challenging scenarios for aerosol medicine. This challenge is …

Therapeutic aerosols are commonly used in mechanically ventilated patients, mainly to
deliver bronchodilator drugs. Because ventilator-supported patients often receive several …