The evolution of biomarkers in thyroid cancer—from mass screening to a personalized biosignature

RH Grogan, EJ Mitmaker, OH Clark - Cancers, 2010 - mdpi.com
Thyroid cancer is the most common malignancy of the endocrine system. The diagnosis of
thyroid nodules, made by neck examination and ultrasonography, is a common event …

Genetic predisposition to familial nonmedullary thyroid cancer: an update of molecular findings and state‐of‐the‐art studies

E Bonora, G Tallini, G Romeo - Journal of oncology, 2010 - Wiley Online Library
Familial thyroid cancer has become a well‐recognized entity in patients with thyroid cancer
originating from follicular cells, that is, nonmedullary thyroid carcinoma. The diagnosis of …

[图书][B] The handbook of biomarkers

KK Jain, KK Jain - 2010 - Springer
There are several definitions of biomarkers. A biomarker is a characteristic that can be
objectively measured and evaluated as an indicator of a physiological as well as a …

Vandetanib in children and adolescents with multiple endocrine neoplasia type 2B associated medullary thyroid carcinoma

E Fox, BC Widemann, MK Chuk, L Marcus, A Aikin… - Clinical Cancer …, 2013 - AACR
Purpose: Medullary thyroid carcinoma (MTC) is a manifestation of multiple endocrine
neoplasia type 2 (MEN2) syndromes caused by germline, activating mutations in the RET …

External validation of three available grading systems for medullary thyroid carcinoma in a single institution cohort

E Vissio, F Maletta, J Fissore, S Osella Abate… - Endocrine …, 2022 - Springer
Medullary thyroid carcinoma (MTC) is a rare thyroid carcinoma with a variable clinical
behavior. Potential clinical and pathological prognostic markers have been investigated, but …

A biomarker and molecular mechanism investigation for thyroid cancer

K Xie - Central European Journal of Immunology, 2023 - termedia.pl
Results: A total of 802 DEGs were obtained between the THCA group and the N group.
These DEGs were mainly enriched in pathways such as lysine degradation. From the PPI …

A review of the significance in measuring preoperative and postoperative carcinoembryonic antigen (CEA) values in patients with medullary thyroid carcinoma (MTC)

I Passos, E Stefanidou, S Meditskou-Eythymiadou… - Medicina, 2021 - mdpi.com
Background and Objectives: Medullary thyroid carcinoma (MTC) accounts for 1–2% of all
thyroid malignancies, and it originates from parafollicular “C” cells. Carcinoembryonic …

Genetic alterations in medullary thyroid cancer: diagnostic and prognostic markers

A Taccaliti, F Silvetti, G Palmonella… - Current …, 2011 - ingentaconnect.com
Medullary thyroid carcinoma (MTC) is a rare calcitonin producing neuroendocrine tumour
that originates from the parafollicular C-cells of the thyroid gland. The RET proto-oncogene …

Clinical performance of calcitonin and procalcitonin Elecsys® immunoassays in patients with medullary thyroid carcinoma

L Giovanella, M Fontana, F Keller… - Clinical Chemistry and …, 2021 - degruyter.com
Objectives Medullary thyroid carcinoma (MTC) is caused by a malignant transformation in
the parafollicular C-cells of the thyroid, where calcitonin (CT) is released. Nowadays, CT is …

Androgen receptor expression in human thyroid cancer tissues: a potential mechanism underlying the gender bias in the incidence of thyroid cancers

JA Stanley, MM Aruldhas, M Chandrasekaran… - The Journal of steroid …, 2012 - Elsevier
Gender bias in the incidence of thyroid cancer is well known, however, the underlying
mechanism is largely unknown. The current study determines variations in the molecular …