[HTML][HTML] Burden of Clostridioides difficile infection (CDI) - a systematic review of the epidemiology of primary and recurrent CDI

E Finn, FL Andersson, M Madin-Warburton - BMC infectious diseases, 2021 - Springer
Background Clostridioides difficile is a Gram-positive anaerobic bacterium, which causes
Clostridioides difficile infection (CDI). It has been recognised as a leading cause of …

Clostridium difficile infection: epidemiology, diagnosis and understanding transmission

JSH Martin, TM Monaghan, MH Wilcox - … reviews Gastroenterology & …, 2016 - nature.com
Clostridium difficile infection (CDI) continues to affect patients in hospitals and communities
worldwide. The spectrum of clinical disease ranges from mild diarrhoea to toxic megacolon …

[HTML][HTML] Clostridium difficile and one health

SC Lim, DR Knight, TV Riley - Clinical Microbiology and Infection, 2020 - Elsevier
Background For over four decades, Clostridium difficile has been a significant enteric
pathogen of humans. It is associated with the use of antimicrobials that generally disrupt the …

Clostridioides difficile Spore Formation and Germination: New Insights and Opportunities for Intervention

A Shen - Annual review of microbiology, 2020 - annualreviews.org
Spore formation and germination are essential for the bacterial pathogen Clostridioides
difficile to transmit infection. Despite the importance of these developmental processes to the …

[HTML][HTML] Fecal microbiota transplantation: donor relation, fresh or frozen, delivery methods, cost-effectiveness

D Ramai, K Zakhia, A Ofosu, E Ofori… - Annals of …, 2019 - ncbi.nlm.nih.gov
Fecal microbiota transplantation (FMT) has evolved into a robust and efficient means for
treating recurrent Clostridium difficile infection (CDI). Our narrative review looks at the donor …

[HTML][HTML] A Pharmacovigilance Study Regarding the Risk of Antibiotic-Associated Clostridioides difficile Infection Based on Reports from the EudraVigilance Database …

BI Vintila, AM Arseniu, C Morgovan, A Butuca, M Sava… - Pharmaceuticals, 2023 - mdpi.com
The Gram-positive anaerobic bacterium Clostridioides difficile (CD) can produce intense
exotoxins, contributing to nosocomial infections, and it is the most common cause of health …

Use of mCherry red fluorescent protein for studies of protein localization and gene expression in Clostridium difficile

EM Ransom, CD Ellermeier… - Applied and …, 2015 - Am Soc Microbiol
Fluorescent proteins are powerful reporters in biology, but most require O2 for chromophore
maturation, making them inherently difficult to use in anaerobic bacteria. Clostridium difficile …

The role of flagella in Clostridium difficile pathogenicity

E Stevenson, NP Minton, SA Kuehne - Trends in microbiology, 2015 - cell.com
Clostridium difficile is widely publicised as a problem in the health-care system. Disruption of
the normal gut microbiota by antibiotic therapy allows C. difficile to colonise the colon. On …

[HTML][HTML] The Environment, Farm Animals and Foods as Sources of Clostridioides difficile Infection in Humans

D Bolton, P Marcos - Foods, 2023 - mdpi.com
The recent discovery of the same Clostridioides difficile ribotypes associated with human
infection in a broad range of environments, animals and foods, coupled with an ever …

Bacteriotherapy for clostridium difficile colitis

EJ Hlavka - US Patent 9,629,881, 2017 - Google Patents
This document discusses, among other things, receiving a plurality of donor fecal samples
from a plurality of donors and storing and indexing each respective donor fecal samples …