[HTML][HTML] 3D printing of hydrogels: Rational design strategies and emerging biomedical applications
Abstract 3D printing alias additive manufacturing can transform 3D virtual models created by
computer-aided design (CAD) into physical 3D objects in a layer-by-layer manner …
computer-aided design (CAD) into physical 3D objects in a layer-by-layer manner …
Heralding a new paradigm in 3D tumor modeling
Numerous studies to date have contributed to a paradigm shift in modeling cancer, moving
from the traditional two-dimensional culture system to three-dimensional (3D) culture …
from the traditional two-dimensional culture system to three-dimensional (3D) culture …
Multi-parametric hydrogels support 3D in vitro bioengineered microenvironment models of tumour angiogenesis
Tumour microenvironment greatly influences the development and metastasis of cancer
progression. The development of three dimensional (3D) culture models which mimic that …
progression. The development of three dimensional (3D) culture models which mimic that …
Glycosaminoglycan-based hydrogels to modulate heterocellular communication in in vitro angiogenesis models
Angiogenesis, the outgrowth of blood vessels, is crucial in development, disease and
regeneration. Studying angiogenesis in vitro remains challenging because the capillary …
regeneration. Studying angiogenesis in vitro remains challenging because the capillary …
A three-dimensional in vitro model of tumor cell intravasation
SM Ehsan, KM Welch-Reardon, ML Waterman… - Integrative …, 2014 - academic.oup.com
Metastasis is the cause of over 90% of all human cancer deaths. Early steps in the
metastatic process include: the formation of new blood vessels, the initiation of epithelial …
metastatic process include: the formation of new blood vessels, the initiation of epithelial …
Tumor-derived microRNA-494 promotes angiogenesis in non-small cell lung cancer
Angiogenesis, a crucial step in tumor growth and metastasis, is regulated by various pro-or
anti-angiogenic factors. Recently, microRNAs have been shown to modulate angiogenic …
anti-angiogenic factors. Recently, microRNAs have been shown to modulate angiogenic …
Hydrogels to model 3D in vitro microenvironment of tumor vascularization
A growing number of failing clinical trials for cancer therapy are substantiating the need to
upgrade the current practice in culturing tumor cells and modeling tumor angiogenesis in …
upgrade the current practice in culturing tumor cells and modeling tumor angiogenesis in …
Proteinaceous hydrogels for bioengineering advanced 3D tumor models
The establishment of tumor microenvironment using biomimetic in vitro models that
recapitulate key tumor hallmarks including the tumor supporting extracellular matrix (ECM) is …
recapitulate key tumor hallmarks including the tumor supporting extracellular matrix (ECM) is …
Engineering a novel 3D printed vascularized tissue model for investigating breast cancer metastasis to bone
Cancer metastases are a challenge for cancer treatment due to their organ specificity and
pathophysiological complexity. Engineering 3D in vitro models capable of replicating native …
pathophysiological complexity. Engineering 3D in vitro models capable of replicating native …
Fibrin stiffness mediates dormancy of tumor-repopulating cells via a Cdc42-driven Tet2 epigenetic program
Y Liu, J Lv, X Liang, X Yin, L Zhang, D Chen, X Jin… - Cancer Research, 2018 - AACR
Dormancy is recognized as a critical biological event for tumorigenic cells surviving in an
extremely harsh environment. Understanding the molecular process of dormancy can unlock …
extremely harsh environment. Understanding the molecular process of dormancy can unlock …