The concentrations of monoamines and cholineacetyl transferase (CAT) are reduced in
brains from patients with normal aging. According to findings about the dopamine (DA) …

Functional 1H magnetic resonance spectroscopy (fMRS) is a derivative of dynamic MRS
imaging. This modality links physiologic metabolic responses with available activity and …

Alzheimer's disease, a major cause of dementia, is characterized by impaired cholinergic
function, increased oxidative stress, and amyloid cascade induction. Sesame lignans have …

Cholinergic dysfunction has been commonly known to be associated with plethora of
neurodegenerative disorders and also serves as a biomarker. Recently, cholinergic system …

ATP: l-methionine S-adenosyltransferase (EC 2.5. 1.6, MAT) activity was analyzed in
erythrocytes from nine patients with a clinical diagnosis of probable Alzheimer's disease …

: Alzheimer's disease (AD) stands as the most prevalent neurodegenerative disorder,
marked by neuronal loss, synaptic dysfunction, atrophy in various brain regions, cognitive …

Substitution of cholinergic drugs in the treatment of Alzheimer type dementia (AD/SDAT) has
hitherto not been very successful. Accumulating data indicate that monoamines are …

Outlines the pharmacological treatment strategies that can be directly related to the
assumed pathophysiology of dementia of the Alzheimer type (DAT). Central-stimulating …

The present study investigated whether stimulation of the GABAergic system affects spatial
navigation [water-maze (WM)] deficit induced by muscarinic blockade (scopolamine). The …

В статье представлена сравнительная оценка динамики показателей когнитивного
функционирования на протяжении годового наблюдения в 3 группах пожилых …