The injured spinal cord does not heal properly. In contrast, tissue repair and functional
recovery occur after skin or muscle injuries. The reason for this dichotomy in wound repair is …

Spinal cord injury (SCI) is one of the most debilitating of all the traumatic conditions that
afflict individuals. For a number of years, extensive studies have been conducted to clarify …

The pathophysiology of acute spinal cord injury (SCI) involves primary and secondary
mechanisms of injury. Though both mechanisms are involved in the neurological …

The complement system plays critical roles in development, homeostasis, and regeneration
in the central nervous system (CNS) throughout life; however, complement dysregulation in …

Free radical formation and oxidative damage have been extensively investigated and
validated as important contributors to the pathophysiology of acute central nervous system …

Spinal cord injury (SCI) can lead to paraplegia or quadriplegia. Although there are no fully
restorative treatments for SCI, various rehabilitative, cellular and molecular therapies have …

Epidural steroid injections (ESIs) are the most widely utilized pain management procedure
in the world, their use supported by more than 45 placebo-controlled studies and dozens of …

Background. Neutralization of central nervous system neurite growth inhibitory factors, for
example, Nogo-A, is a promising approach to improving recovery following spinal cord injury …

Reactive oxygen species (ROS) are produced at low levels in mammalian cells by various
metabolic processes, such as oxidative phosphorylation by the mitochondrial respiratory …

Spinal cord injury (SCI), as one of the intractable diseases in clinical medicine, affects
thousands of human beings, and the pathologic changes after injury have been a hot spot …