Global trends in hepatocellular carcinoma epidemiology: implications for screening, prevention and therapy
Hepatocellular carcinoma (HCC) mortality rates are increasing globally, and particularly in
the Western world. Cirrhosis remains the predominant risk factor for HCC. However …
the Western world. Cirrhosis remains the predominant risk factor for HCC. However …
Epidemiology and risk-stratification of NAFLD-associated HCC
GN Ioannou - Journal of hepatology, 2021 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is projected to become the leading cause of
hepatocellular carcinoma (HCC) in many countries. Many risk factors for NAFLD are also …
hepatocellular carcinoma (HCC) in many countries. Many risk factors for NAFLD are also …
AASLD practice guidance on prevention, diagnosis, and treatment of hepatocellular carcinoma
This guidance document provides an updated approach to the prevention, diagnosis, and
treatment of hepatocellular carcinoma (HCC). The prior American Association for the Study …
treatment of hepatocellular carcinoma (HCC). The prior American Association for the Study …
Current therapies and new developments in NASH
Non-alcoholic steatohepatitis is becoming the most important aetiology for advanced liver
disease. There has been important progress in the field in recent years and the complexity of …
disease. There has been important progress in the field in recent years and the complexity of …
Targeting cancer-promoting inflammation—have anti-inflammatory therapies come of age?
The immune system has crucial roles in cancer development and treatment. Whereas
adaptive immunity can prevent or constrain cancer through immunosurveillance, innate …
adaptive immunity can prevent or constrain cancer through immunosurveillance, innate …
Trial design and endpoints in hepatocellular carcinoma: AASLD consensus conference
Hepatocellular carcinoma (HCC) is the fourth leading cause of cancer-related mortality
worldwide.(1, 2) This neoplasm has some unique characteristics. It occurs in most cases …
worldwide.(1, 2) This neoplasm has some unique characteristics. It occurs in most cases …
Side effects of statins: from pathophysiology and epidemiology to diagnostic and therapeutic implications
Abstract Treatment with statins, inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A
reductase, has proven beneficial preventive effects on cardiovascular events. However …
reductase, has proven beneficial preventive effects on cardiovascular events. However …
Fibrosis regression after eradication of hepatitis C virus: from bench to bedside
DC Rockey, SL Friedman - Gastroenterology, 2021 - Elsevier
Hepatitis C virus (HCV) infection and its complications have been the major cause of
cirrhosis and its complications for several decades in the Western world. Until recently …
cirrhosis and its complications for several decades in the Western world. Until recently …
Non-alcoholic fatty liver disease in children and young adults is associated with increased long-term mortality
TG Simon, B Roelstraete, K Hartjes, U Shah… - Journal of …, 2021 - Elsevier
Background & Aims Longitudinal data are scarce regarding the natural history and long-term
risk of mortality in children and young adults with biopsy-confirmed non-alcoholic fatty liver …
risk of mortality in children and young adults with biopsy-confirmed non-alcoholic fatty liver …
Cirrhosis as new indication for statins
In the recent years, there have been an increasing number of reports on favourable effects of
statins in patients with advanced chronic liver disease. These include reduction in portal …
statins in patients with advanced chronic liver disease. These include reduction in portal …