Niemann–Pick type C (NPC) disease is a rare autosomal recessive inherited childhood
neurodegenerative disease characterized by the accumulation of cholesterol and …

Niemann-Pick type C (NPC) disease is a lysosomal storage disorder characterized by
cholesterol accumulation caused by loss-of-function mutations in the Npc1 gene. NPC …

Red fluorescent hybrid nanoparticles (NPG@ PFBD) have been designed and synthesized
successfully. The NPG@ PFBD nanoparticles are composed of a fluorescent …

The increased demand for cholesterol to support cancer growth and progression is often
associated with elevated uptake of cholesterol from low density lipoproteins (LDL). Once …

Cell-to-cell propagation of protein aggregates has been implicated in the progression of
neurodegenerative diseases. However, the underlying mechanism and modulators of this …

Mitochondrial dysfunction and steroidogenesis in Parkinson disease Page 1 University of
Calgary PRISM Repository https://prism.ucalgary.ca The Vault Open Theses and Dissertations …

Lysosomal storage disorders (LSDs) are a family composed of more than 60 inherited
metabolic disorders characterized by the accumulation of uncatabolized materials within the …

Reduction/oxidation-dependent reactions affect many cellular functional pathways.
Mitochondria are at the center of these processes, as mitochondria both generate reactive …

The common impression of relating bad mutations of organisms to exposure to a magnetic
field, is not significantly appropriate. We have demonstrated that a magnetic field can …