[HTML][HTML] Integrative omics approaches for biosynthetic pathway discovery in plants

KS Singh, JJJ van der Hooft, SCM van Wees… - Natural Product …, 2022 - pubs.rsc.org
Covering: up to 2022 With the emergence of large amounts of omics data, computational
approaches for the identification of plant natural product biosynthetic pathways and their …

Metabolomics meets systems immunology

J Fu, F Zhu, CJ Xu, Y Li - EMBO reports, 2023 - embopress.org
Metabolic processes play a critical role in immune regulation. Metabolomics is the
systematic analysis of small molecules (metabolites) in organisms or biological samples …

Metabolomics reveal nanoplastic-induced mitochondrial damage in human liver and lung cells

S Lin, H Zhang, C Wang, XL Su, Y Song… - … science & technology, 2022 - ACS Publications
Plastic debris in the global biosphere is an increasing concern, and nanoplastic (NPs)
toxicity in humans is far from being understood. Studies have indicated that NPs can affect …

[HTML][HTML] Metabolomics and chemometrics: The next-generation analytical toolkit for the evaluation of food quality and authenticity

P Garcia-Perez, PP Becchi, L Zhang… - Trends in Food Science …, 2024 - Elsevier
Background The advances in NMR and mass spectrometry metabolomics allows a
comprehensive profiling of foods, potentially covering geographical origin, authenticity …

Integration of metabolomics, lipidomics, and proteomics reveals the metabolic characterization of nonalcoholic steatohepatitis

J Zhang, Y Yang, Z Wang, X Zhang… - Journal of Proteome …, 2023 - ACS Publications
Metabolic dysfunction is associated with nonalcoholic steatohepatitis (NASH) development.
However, omics studies investigating metabolic changes in NASH patients are limited. In …

Methods for quantifying the metabolic boundary fluxes of cell cultures in large cohorts by high-resolution hydrophilic liquid chromatography mass spectrometry

RA Groves, M Mapar, R Aburashed, LF Ponce… - Analytical …, 2022 - ACS Publications
Metabolomics is a mainstream approach for investigating the metabolic underpinnings of
complex biological phenomena and is increasingly being applied to large-scale studies …

Mass spectrometry‐based metabolomic analysis as a tool for quality control of natural complex products

L Mattoli, M Gianni, M Burico - Mass Spectrometry Reviews, 2023 - Wiley Online Library
Metabolomics is an area of intriguing and growing interest. Since the late 1990s, when the
first Omic applications appeared to study metabolite's pool (“metabolome”), to understand …

[HTML][HTML] Triangulating nutrigenomics, metabolomics and microbiomics toward personalized nutrition and healthy living

G Lagoumintzis, GP Patrinos - Human Genomics, 2023 - Springer
The unique physiological and genetic characteristics of individuals influence their reactions
to different dietary constituents and nutrients. This notion is the foundation of personalized …

[HTML][HTML] Model-driven insights into the effects of temperature on metabolism

P Wendering, Z Nikoloski - Biotechnology Advances, 2023 - Elsevier
Temperature affects cellular processes at different spatiotemporal scales, and identifying the
genetic and molecular mechanisms underlying temperature responses paves the way to …

[HTML][HTML] Amino acid signature of oxidative stress in patients with type 2 diabetes: targeted exploratory metabolomic research

CG Bala, A Rusu, D Ciobanu, C Bucsa, G Roman - Antioxidants, 2021 - mdpi.com
Oxidative stress plays a key role in the development of chronic diabetes-related
complications. Previous metabolomic studies showed a positive association of diabetes and …