Castration-resistant prostate cancer (CRPC), especially metastatic castration-resistant
prostate cancer (mCRPC) is one of the most prevalent malignancies and main cause of …

Abstract Traditional Chinese Medicine (TCM) has the characteristics of multiple targets,
slight side effects and good therapeutic effects. Good anti-tumor effects are shown by …

Collective cancer invasion with leader–follower organization is increasingly recognized as a
predominant mechanism in the metastatic cascade. Leader cells support cancer invasion by …

Immunotherapy based on immune checkpoint inhibitors has evolved into a new pillar of
cancer treatment in clinics, but dealing with treatment resistance (either primary or acquired) …

The exact mechanistic understanding of cancer metastasis continues to be unknown,
although it is a major cause of death worldwide. Along with the tumor mass, the tumor …

Colorectal cancer (CRC) represents one of the most common cancers worldwide, with a
high mortality rate despite the decreasing incidence and new diagnostic and therapeutic …

The migration and invasion of cancer cells through 3D confined extracellular matrices is
coupled to cell mechanics and the mechanics of the extracellular matrix. Cell mechanics is …

Background: The oral microbiome may play an important role in colorectal carcinogenesis.
However, few studies have investigated the association between oral microbiome and the …

Cell migration and invasion is a key driving factor for providing essential cellular functions
under physiological conditions or the malignant progression of tumors following downward …

Biological materials such as extracellular matrix scaffolds, cancer cells, and tissues are often
assumed to respond elastically for simplicity; the viscoelastic response is quite commonly …