X-linked agammaglobulinemia (XLA) is a rare primary immunodeficiency disorder. It occurs
in around one in 200,000 live births and is caused by mutations in the Bruton Tyrosine …

Common variable immunodeficiency (CVID) is a primary immunodeficiency disorder that
causes decreased immunity and increased susceptibility to infections. It affects B lymphocyte …

3.1. Introducción a las Inmunodeficiencias Primarias……………………………………………...
29 3.2. Introducción a la Inmunodeficiencia Común Variable …

Background The respiratory tract microbiome is essential for human health and well-being
and is determined by genetic, lifestyle, and environmental factors. Patients with Common …

Background: Granulomatous–lymphocytic interstitial lung disease (GLILD) is a rare,
potentially severe pulmonary complication of common variable immunodeficiency disorders …

Method: To address this question, I employed our recently developed lipodystrophic mouse
model, in which adipocyte MDM2 is genetically deleted (so-called Adipo-MDM2-KO mice) …

The human microbiome is a growing area of research. Enabled by advances in sequencing
techniques, vast amounts of microbiome data are being generated. Using this data to …

Immunoglobulin A (IgA) is the most prevalent antibody at mucosal surfaces, where it helps to
maintain homeostasis [1]. It has been viewed traditionally as a silent housekeeping antibody …

The human microbiome consists of the microorganisms associated with the body, such as
bacteria, fungi, archaea, protozoa, and viruses, along with their gene content and products …