Small RNAs, large networks: posttranscriptional regulons in gram-negative bacteria
K Papenfort, S Melamed - Annual review of microbiology, 2023 - annualreviews.org
Small regulatory RNA (sRNAs) are key mediators of posttranscriptional gene control in
bacteria. Assisted by RNA-binding proteins, a single sRNA often modulates the expression …
bacteria. Assisted by RNA-binding proteins, a single sRNA often modulates the expression …
Metal homeostasis and resistance in bacteria
P Chandrangsu, C Rensing, JD Helmann - Nature Reviews …, 2017 - nature.com
Metal ions are essential for many reactions, but excess metals can be toxic. In bacteria,
metal limitation activates pathways that are involved in the import and mobilization of metals …
metal limitation activates pathways that are involved in the import and mobilization of metals …
Dual RNA-seq unveils noncoding RNA functions in host–pathogen interactions
Bacteria express many small RNAs for which the regulatory roles in pathogenesis have
remained poorly understood due to a paucity of robust phenotypes in standard virulence …
remained poorly understood due to a paucity of robust phenotypes in standard virulence …
Antibiotics induce redox-related physiological alterations as part of their lethality
DJ Dwyer, PA Belenky, JH Yang… - Proceedings of the …, 2014 - National Acad Sciences
Deeper understanding of antibiotic-induced physiological responses is critical to identifying
means for enhancing our current antibiotic arsenal. Bactericidal antibiotics with diverse …
means for enhancing our current antibiotic arsenal. Bactericidal antibiotics with diverse …
Small RNAs in bacteria and archaea: who they are, what they do, and how they do it
EGH Wagner, P Romby - Advances in genetics, 2015 - Elsevier
Small RNAs are ubiquitously present regulators in all kingdoms of life. Most bacterial and
archaeal small RNAs (sRNAs) act by antisense mechanisms on multiple target mRNAs …
archaeal small RNAs (sRNAs) act by antisense mechanisms on multiple target mRNAs …
Regulation by small RNAs in bacteria: expanding frontiers
Research on the discovery and characterization of small, regulatory RNAs in bacteria has
exploded in recent years. These sRNAs act by base pairing with target mRNAs with which …
exploded in recent years. These sRNAs act by base pairing with target mRNAs with which …
Dual RNA-seq of pathogen and host
AJ Westermann, SA Gorski, J Vogel - Nature Reviews Microbiology, 2012 - nature.com
A comprehensive understanding of host–pathogen interactions requires a knowledge of the
associated gene expression changes in both the pathogen and the host. Traditional, probe …
associated gene expression changes in both the pathogen and the host. Traditional, probe …
Hfq and its constellation of RNA
J Vogel, BF Luisi - Nature Reviews Microbiology, 2011 - nature.com
Hfq is an RNA-binding protein that is common to diverse bacterial lineages and has key
roles in the control of gene expression. By facilitating the pairing of small RNAs with their …
roles in the control of gene expression. By facilitating the pairing of small RNAs with their …
Transcriptional regulation by Ferric Uptake Regulator (Fur) in pathogenic bacteria
B Troxell, HM Hassan - Frontiers in cellular and infection microbiology, 2013 - frontiersin.org
In the ancient anaerobic environment, ferrous iron (Fe2+) was one of the first metal
cofactors. Oxygenation of the ancient world challenged bacteria to acquire the insoluble …
cofactors. Oxygenation of the ancient world challenged bacteria to acquire the insoluble …
Cell death from antibiotics without the involvement of reactive oxygen species
Y Liu, JA Imlay - Science, 2013 - science.org
Recent observations have suggested that classic antibiotics kill bacteria by stimulating the
formation of reactive oxygen species (ROS). If true, this notion might guide new strategies to …
formation of reactive oxygen species (ROS). If true, this notion might guide new strategies to …