[HTML][HTML] Detection of viral infections by innate immunity
Pattern recognition receptors (PRRs) and inflammasomes are a key part of the anti-viral
innate immune system as they detect conserved viral pathogen-associated molecular …
innate immune system as they detect conserved viral pathogen-associated molecular …
Magnetic nanoparticles in targeted drug delivery: a review
E Kianfar - Journal of Superconductivity and Novel Magnetism, 2021 - Springer
Magnetic nanoparticles are one of the most important and widely used types of
nanomaterials, whose unique properties make them special compared to other …
nanomaterials, whose unique properties make them special compared to other …
A candidate multi-epitope vaccine against SARS-CoV-2
T Kar, U Narsaria, S Basak, D Deb, F Castiglione… - Scientific reports, 2020 - nature.com
In the past two decades, 7 coronaviruses have infected the human population, with two
major outbreaks caused by SARS-CoV and MERS-CoV in the year 2002 and 2012 …
major outbreaks caused by SARS-CoV and MERS-CoV in the year 2002 and 2012 …
[HTML][HTML] Evolution of Toll-like receptor 7/8 agonist therapeutics and their delivery approaches: From antiviral formulations to vaccine adjuvants
Imidazoquinoline derivatives (IMDs) and related compounds function as synthetic agonists
of Toll-like receptors 7 and 8 (TLR7/8) and one is FDA approved for topical antiviral and skin …
of Toll-like receptors 7 and 8 (TLR7/8) and one is FDA approved for topical antiviral and skin …
Host-directed antiviral therapy
Antiviral drugs have traditionally been developed by directly targeting essential viral
components. However, this strategy often fails due to the rapid generation of drug-resistant …
components. However, this strategy often fails due to the rapid generation of drug-resistant …
Toll-like receptors in the vascular system: sensing the dangers within
S Goulopoulou, CG McCarthy, RC Webb - Pharmacological reviews, 2016 - ASPET
Toll-like receptors (TLRs) are components of the innate immune system that respond to
exogenous infectious ligands (pathogen-associated molecular patterns, PAMPs) and …
exogenous infectious ligands (pathogen-associated molecular patterns, PAMPs) and …
Toll-like receptors as a therapeutic target in the era of immunotherapies
Toll-like receptors (TLRs) are the pattern recognition receptors, which are activated by
foreign and host molecules in order to initiate the immune response. They play a crucial role …
foreign and host molecules in order to initiate the immune response. They play a crucial role …
Antiviral strategies targeting host factors and mechanisms obliging+ ssRNA viral pathogens
The ongoing COVID-19 pandemic, periodic recurrence of viral infections, and the
emergence of challenging variants has created an urgent need of alternative therapeutic …
emergence of challenging variants has created an urgent need of alternative therapeutic …
Flattening the COVID-19 curve with natural killer cell based immunotherapies
M Market, L Angka, AB Martel, D Bastin… - Frontiers in …, 2020 - frontiersin.org
Natural Killer (NK) cells are innate immune responders critical for viral clearance and
immunomodulation. Despite their vital role in viral infection, the contribution of NK cells in …
immunomodulation. Despite their vital role in viral infection, the contribution of NK cells in …
Targeting toll-like receptor 7/8 for immunotherapy: recent advances and prospectives
H Sun, Y Li, P Zhang, H Xing, S Zhao, Y Song… - Biomarker …, 2022 - Springer
Toll-like receptors (TLRs) are a large family of proteins that are expressed in immune cells
and various tumor cells. TLR7/8 are located in the intracellular endosomes, participate in …
and various tumor cells. TLR7/8 are located in the intracellular endosomes, participate in …