Acute kidney injury by ischemia/reperfusion and extracellular vesicles

MØ Nørgård, P Svenningsen - International Journal of Molecular Sciences, 2023 - mdpi.com
Acute kidney injury (AKI) is often caused by ischemia-reperfusion injury (IRI). IRI significantly
affects kidney metabolism, which elicits pro-inflammatory responses and kidney injury. The …

Extracellular vesicles: illuminating renal pathophysiology and therapeutic frontiers

L Shi, H Zeng, Z An, W Chen, Y Shan, C Ji… - European Journal of …, 2024 - Elsevier
Extracellular vesicles (EVs) are minute sacs released by cells into the extracellular milieu,
harboring an array of biomolecules including proteins, nucleic acids, and lipids. Notably, a …

Choline Phosphate-Grafted Nanozymes as Universal Extracellular Vesicle Probes for Bladder Cancer Detection

Q Li, S Zhan, X Yang, Z Zhang, N Sun, X Wang… - ACS …, 2024 - ACS Publications
Urinary extracellular vesicles (uEVs) are regarded as highly promising liquid-biopsy
biomarkers for the early diagnosis and prognosis of bladder cancer (BC). However …

Capturing the Kidney Transcriptome by Urinary Extracellular Vesicles—From Pre-Analytical Obstacles to Biomarker Research

K Barreiro, OP Dwivedi, A Rannikko, H Holthöfer… - Genes, 2023 - mdpi.com
Urinary extracellular vesicles (uEV) hold non-invasive RNA biomarkers for genitourinary
tract diseases. However, missing knowledge about reference genes and effects of …

Maternal exposure to E 551 during pregnancy leads to genome-wide DNA methylation changes and metabolic disorders in the livers of pregnant mice and their …

Y Zhan, H Lou, R Shou, A Li, J Shang, Y Jin, L Li… - Journal of Hazardous …, 2024 - Elsevier
The widespread use of nanoparticles in the food industry has raised concerns regarding
their potential adverse effects on human health, particularly in vulnerable populations …

The onset of adenosine monophosphate‐activated protein kinase activity on orthodontic tooth movement in rats with type 2 diabetes

D Huang, Y Li, S Chen, H Wang, Y Jiang… - European Journal of …, 2023 - Wiley Online Library
Adenosine monophosphate‐activated protein kinase (AMPK) plays pivotal roles in
metabolic diseases including type 2 diabetes. However, the specific role of AMPK for …

Tetraspanin immunoassay for the detection of extracellular vesicles and renal cell carcinoma

M Khan, MK Islam, M Rahman, B Dhondt… - Nano …, 2024 - Wiley Online Library
Half of patients with renal cell carcinoma (RCC) develop metastases. New and noninvasive
biomarkers are needed for the diagnosis of RCC. The study aims to develop an EV‐based …