Animal models of drug-induced pulmonary fibrosis: an overview of molecular mechanisms and characteristics

S Li, J Shi, H Tang - Cell Biology And Toxicology, 2022 - Springer
Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease characterized by
progressive loss of pulmonary function. Drug-induced interstitial lung disease has been …

The protective effects of chrysin on cadmium-induced pulmonary toxicity; a multi-biomarker approach

N Akaras, M Ileriturk, C Gur, S Kucukler, M Oz… - … Science and Pollution …, 2023 - Springer
This study aimed to determine the potential protective effects of chrysin (CHR) on
experimental cadmium (Cd)-induced lung toxicity in rats. To this end, rats were divided into …

The protective potential of alpha lipoic acid on amiodarone-induced pulmonary fibrosis and hepatic injury in rats

G Ibrahim Fouad, M R. Mousa - Molecular and Cellular Biochemistry, 2021 - Springer
Amiodarone (AMD) is a widely used antiarrhythmic drug prescribed to treat cardiac
tachyarrhythmias; however, AMD has been reported to provoke pulmonary fibrosis (PF) and …

[HTML][HTML] Amiodarone induces cell proliferation and myofibroblast differentiation via ERK1/2 and p38 MAPK signaling in fibroblasts

J Weng, M Tu, P Wang, X Zhou, C Wang, X Wan… - Biomedicine & …, 2019 - Elsevier
Amiodarone is a potent antidysrhythmic agent that can cause potentially life-threatening
pulmonary fibrosis. Accumulating evidence has demonstrated that myofibroblast …

The inhibitory mechanisms of losartan and vitamin D on amiodarone‐induced lung inflammation in rats: Role of mitogen‐activated protein kinases/activator protein‐1

S Al‐Hassan, H Attia, H Alomar… - Journal of Biochemical …, 2021 - Wiley Online Library
Amiodarone (AMD), an antiarrhythmic drug, is used cautiously due to its lung toxicity that is
characterized by alveolar inflammation followed by fatal fibrosis. AMD induces lung …

Crucial role of PLGA nanoparticles in mitigating the amiodarone-induced pulmonary toxicity

A Motawea, DAM Ahmed, AA El-Mansy… - International Journal of …, 2021 - Taylor & Francis
Background Amiodarone (AMD) is a widely used anti-arrhythmic drug, but its administration
could be associated with varying degrees of pulmonary toxicity. In attempting to circumvent …

[HTML][HTML] Insights into the actions of angiotensin-1 receptor (AT1R) inverse agonists: Perspectives and implications in COVID-19 treatment

L Heimfarth, MA Dos Santos, JA Barreto-Filho… - EXCLI …, 2021 - ncbi.nlm.nih.gov
Abstract New coronavirus SARS-CoV-2 (COVID-19) has caused chaos in health care
systems. Clinical manifestations of COVID-19 are variable, with a complex pathophysiology …

[PDF][PDF] Protection against lung toxicity induced by Amiodarone in Albino rats by fish oil

NA Sarg, KM Kamal - Journal of American Science, 2019 - bu.edu.eg
Background: Amiodarone (AD) is a strong anti-arrhythmic drug but has adverse reactions on
different organs. Fish oil which is rich in Omega-3 polyunsaturated fatty acids (omega-3 …

[HTML][HTML] Protocol for a prospective multicenter cross-sectional observational study to investigate the role of air pollution on allergic rhinitis prevalence

J Liu, Y Wang, S Liu, S Cao, C Xu, M Zhang, S Liu - Medicine, 2020 - journals.lww.com
Discussion: This study will provide correlation of NO 2, SO 2, PM10, and PM2. 5 for AR in
several aspects, including symptom score, drug score, quality of life score, asthma control …

[PDF][PDF] POTENSI ROSUVASTATIN SEBAGAI AGEN ANTIFIBROTIK: KAJIAN TERHADAP KADAR SUPEROXIDE DISMUTASE DAN PRESENTASE AREA SERABUT …

D Pakaya, M Salma, Y Fitriana, S Anwar… - LAMBUNG …, 2023 - fk.ulm.ac.id
ABSTRAK Latar Belakang: Peradangan kronis pada jaringan paru dapat memicu deposisi
kolagen dan matriks ekstraseluler dengan hasil akhir fibrosis. Rosuvastatin memiliki efek …