While there exist some long non-coding RNAs (lncRNAs) that are structurally similar to
mRNAs (capped, spliced, poly a tail), not all of the lncRNAs exhibit these features …

Over the past decade, it has become clear that mammalian genomes encode thousands of
long non-coding RNAs (lncRNAs), many of which are now implicated in diverse biological …

Mammalian genomes are pervasively transcribed, to produce thousands of long non-coding
RNAs (lncRNAs),. A few of these lncRNAs have been shown to recruit regulatory complexes …

INTRODUCTION The human genome contains tens of thousands of loci that produce long
noncoding RNAs (lncRNAs), transcripts that have no apparent protein-coding potential. A …

The human genome contains thousands of long non-coding RNAs, but specific biological
functions and biochemical mechanisms have been discovered for only about a dozen,,,,–. A …

Although many long noncoding RNAs (lncRNAs) have been identified in human and other
mammalian genomes, there has been limited systematic functional characterization of these …

Long non-coding RNAs (lncRNAs) have emerged in recent years as major players in a
multitude of pathways across species, but it remains challenging to understand which of …

Whole transcriptome sequencing (RNA-seq) has become a standard for cataloguing and
monitoring RNA populations. One of the main bottlenecks, however, is to correctly identify …

Crucial transitions in cancer—including tumor initiation, local expansion, metastasis, and
therapeutic resistance—involve complex interactions between cells within the dynamic …

The central dogma of gene expression propounds that DNA is transcribed to mRNA and
finally gets translated into protein. Only 2–3% of the genomic DNA is transcribed to protein …