An image analysis method for the precise selection and quantitation of fluorescently labeled cellular constituents: application to the measurement of human muscle …

CC Agley, CP Velloso, NR Lazarus… - … of Histochemistry & …, 2012 - journals.sagepub.com
The accurate measurement of the morphological characteristics of cells with nonuniform
conformations presents difficulties. We report here a straightforward method using …

1, 25 (OH) 2vitamin D3 enhances myogenic differentiation by modulating the expression of key angiogenic growth factors and angiogenic inhibitors in C2C12 skeletal …

LA Garcia, MG Ferrini, KC Norris, JN Artaza - The Journal of steroid …, 2013 - Elsevier
Vitamin D is mostly recognized for its regulation of calcium homeostasis in relation to the
intestine, kidney, and bone. Although clinical studies have linked vitamin D with increased …

Vitamin D and muscle sarcopenia in aging

B Abiri, M Vafa - Clinical and Preclinical Models for Maximizing …, 2020 - Springer
Sarcopenia, the age-dependent decline of muscle mass and performance, is a common
condition among elderly population and is related to numerous adverse health outcomes …

Vitamin D and skeletal muscle: current concepts from preclinical studies

CM Girgis, TC Brennan Speranza - Journal of Bone and Mineral …, 2021 - academic.oup.com
Muscle weakness has been recognized as a hallmark feature of vitamin D deficiency for
many years. Until recently, the direct biomolecular effects of vitamin D on skeletal muscle …

[HTML][HTML] Dose-dependent effects of vitamin D on transdifferentiation of skeletal muscle cells to adipose cells

KJP Ryan, ZCTR Daniel, LJL Craggs… - The Journal of …, 2013 - ncbi.nlm.nih.gov
Fat infiltration within muscle is one of a number of features of vitamin D deficiency, which
leads to a decline in muscle functionality. The origin of this fat is unclear, but one possibility …

The common mechanisms of sarcopenia and NAFLD

Y Zhai, Q Xiao - BioMed research international, 2017 - Wiley Online Library
Current studies have shown that sarcopenia and nonalcoholic fatty liver disease (NAFLD)
have similar pathophysiological profiles. The cooccurrence of sarcopenia and NAFLD has …

Recent advances in pharmacological, hormonal, and nutritional intervention for sarcopenia

K Sakuma, A Yamaguchi - Pflügers Archiv-European Journal of Physiology, 2018 - Springer
Sarcopenia, the age-related loss of skeletal muscle mass, is characterized by a deterioration
of muscle quantity and quality leading to a gradual slowing of movement, a decline in …

Interaction of vitamin D with membrane-based signaling pathways

MJ Larriba, JM González-Sancho, F Bonilla… - Frontiers in …, 2014 - frontiersin.org
Many studies in different biological systems have revealed that 1α, 25-dihydroxyvitamin D3
(1α, 25 (OH) 2D3) modulates signaling pathways triggered at the plasma membrane by …

Effects of 1,25(OH)2D3 and 25(OH)D3 on C2C12 Myoblast Proliferation, Differentiation, and Myotube Hypertrophy

K Van der Meijden, N Bravenboer… - Journal of Cellular …, 2016 - Wiley Online Library
An adequate vitamin D status is essential to optimize muscle strength. However, whether
vitamin D directly reduces muscle fiber atrophy or stimulates muscle fiber hypertrophy …

Current thoughts of notch's role in myoblast regulation and muscle-associated disease

JC Gerrard, JP Hay, RN Adams, JC Williams III… - International Journal of …, 2021 - mdpi.com
The evolutionarily conserved signaling pathway Notch is unequivocally essential for
embryogenesis. Notch's contribution to the muscle repair process in adult tissue is complex …