Brain metastases affect a significant percentage of patients with advanced extracranial
malignancies. Yet, the incidence of brain metastases remains poorly described, largely due …

The present review aimed to establish an understanding of the pathophysiology of
leptomeningeal disease as it relates to late-stage development among different cancer …

Background Treatment options for patients with melanoma brain metastasis (MBM) have
changed significantly in the last decade. Few studies have evaluated changes in outcomes …

Objective Radiation therapy is a cornerstone of brain metastasis (BrM) management but
carries the risk of radiation necrosis (RN), which can require resection for palliation or …

Abstract Purpose of Review Leptomeningeal disease (LMD) is a devastating complication of
advanced metastatic cancer associated with a poor prognosis and limited treatment options …

Importance Adjuvant stereotactic radiosurgery (SRS) enhances the local control of resected
brain metastases (BrM). However, the risks of local failure (LF) and potential for …

Simple Summary Brain metastases are the most common brain tumor in adults and are
associated with poor prognosis. The propensity of different solid tumors to metastasize …

Purpose The efficacy of salvage resection (SR) of recurrent brain metastases (rBrM)
following stereotactic radiosurgery (SRS) is undefined. We sought to describe local …

Importance Brain metastasis (BM) is the most common malignant intracranial neoplasm in
adults with over 100,000 new cases annually in the United States and outnumbering primary …

Brain metastases are the most common brain malignancy. This review discusses the studies
presented at the third annual meeting of the Melanoma Research Foundation in the context …