[HTML][HTML] Role of oxidative stress in male infertility: an updated review

AT Alahmar - Journal of human reproductive sciences, 2019 - journals.lww.com
Current evidence links oxidative stress (OS) to male infertility, reduced sperm motility, sperm
DNA damage and increased risk of recurrent abortions and genetic diseases. A review of …

Sperm DNA fragmentation testing: Summary evidence and clinical practice recommendations

SC Esteves, A Zini, RM Coward, DP Evenson… - Andrologia, 2021 - Wiley Online Library
We herein summarise the evidence concerning the impact of sperm DNA fragmentation in
various clinical infertility scenarios and the advances on sperm DNA fragmentation tests …

Heavy metal and metalloid-induced reproductive toxicity

AG Mukherjee, UR Wanjari, K Renu, B Vellingiri… - Environmental …, 2022 - Elsevier
Heavy metals and metalloid exposure are among the most common factors responsible for
reproductive toxicity in human beings. Several studies have indicated that numerous metals …

[HTML][HTML] Exploring the evidence for epigenetic regulation of environmental influences on child health across generations

CV Breton, R Landon, LG Kahn, MB Enlow… - Communications …, 2021 - nature.com
Environmental exposures, psychosocial stressors and nutrition are all potentially important
influences that may impact health outcomes directly or via interactions with the genome or …

[HTML][HTML] Effect of oxidative stress on male reproduction

A Agarwal, G Virk, C Ong… - The world journal of …, 2014 - synapse.koreamed.org
Infertility affects approximately 15% of couples trying to conceive, and a male factor
contributes to roughly half of these cases. Oxidative stress (OS) has been identified as one …

[HTML][HTML] Male subfertility and oxidative stress

EPP Evans, JTM Scholten, A Mzyk… - Redox biology, 2021 - Elsevier
To date 15% of couples are suffering from infertility with 45–50% of males being
responsible. With an increase in paternal age as well as various environmental and lifestyle …

[HTML][HTML] Sperm selection for ICSI: do we have a winner?

D Baldini, D Ferri, GM Baldini, D Lot, A Catino… - Cells, 2021 - mdpi.com
In assisted reproductive technology (ART), the aim of sperm cells' preparation is to select
competent spermatozoa with the highest fertilization potential and in this context, the …

[HTML][HTML] Experimental heatwaves compromise sperm function and cause transgenerational damage in a model insect

K Sales, R Vasudeva, ME Dickinson, JL Godwin… - Nature …, 2018 - nature.com
Climate change is affecting biodiversity, but proximate drivers remain poorly understood.
Here, we examine how experimental heatwaves impact on reproduction in an insect system …

Sperm DNA damage caused by oxidative stress: modifiable clinical, lifestyle and nutritional factors in male infertility

C Wright, S Milne, H Leeson - Reproductive biomedicine online, 2014 - Elsevier
DNA fragmentation is an important factor in the aetiology of male infertility. However, it is still
underevaluated and its inclusion in routine semen analysis is debated. DNA fragmentation …

The landscape of somatic mutation in cerebral cortex of autistic and neurotypical individuals revealed by ultra-deep whole-genome sequencing

RE Rodin, Y Dou, M Kwon, MA Sherman… - Nature …, 2021 - nature.com
We characterize the landscape of somatic mutations—mutations occurring after fertilization—
in the human brain using ultra-deep (~ 250×) whole-genome sequencing of prefrontal cortex …