Exercise mimetics: harnessing the therapeutic effects of physical activity
Exercise mimetics are a proposed class of therapeutics that specifically mimic or enhance
the therapeutic effects of exercise. Increased physical activity has demonstrated positive …
the therapeutic effects of exercise. Increased physical activity has demonstrated positive …
Functional and/or structural brain changes in response to resistance exercises and resistance training lead to cognitive improvements–a systematic review
Background During the aging process, physical capabilities (eg, muscular strength) and
cognitive functions (eg, memory) gradually decrease. Regarding cognitive functions …
cognitive functions (eg, memory) gradually decrease. Regarding cognitive functions …
Effect of early mobilisation on long-term cognitive impairment in critical illness in the USA: a randomised controlled trial
Background Patients who have received mechanical ventilation can have prolonged
cognitive impairment for which there is no known treatment. We aimed to establish whether …
cognitive impairment for which there is no known treatment. We aimed to establish whether …
Sarcopenia and cognitive function: role of myokines in muscle brain cross-talk
L Scisciola, RA Fontanella, Surina, V Cataldo… - Life, 2021 - mdpi.com
Sarcopenia is a geriatric syndrome characterized by the progressive degeneration of muscle
mass and function, and it is associated with severe complications, which are falls, functional …
mass and function, and it is associated with severe complications, which are falls, functional …
Effects of aerobic exercise training on systemic biomarkers and cognition in late middle-aged adults at risk for Alzheimer's disease
Increasing evidence indicates that physical activity and exercise training may delay or
prevent the onset of Alzheimer's disease (AD). However, systemic biomarkers that can …
prevent the onset of Alzheimer's disease (AD). However, systemic biomarkers that can …
Irisin, an exercise-induced bioactive peptide beneficial for health promotion during aging process
Irisin is an exercise-induced myokine expressed as a bioactive peptide in multiple tissues
and organs, and exercise and cold exposure are the major inducers for its secretion. Irisin …
and organs, and exercise and cold exposure are the major inducers for its secretion. Irisin …
Exercise-released myokines in the control of energy metabolism
C Laurens, A Bergouignan, C Moro - Frontiers in physiology, 2020 - frontiersin.org
Physical activity reduces cardiometabolic risk, while physical inactivity increases chronic
diseases risk. This led to the idea that exercise-induced muscle contraction contributes to …
diseases risk. This led to the idea that exercise-induced muscle contraction contributes to …
Sarcopenia and Cognitive decline in older adults: targeting the muscle–brain Axis
Declines in physical performance and cognition are commonly observed in older adults. The
geroscience paradigm posits that a set of processes and pathways shared among age …
geroscience paradigm posits that a set of processes and pathways shared among age …
FNDC5/Irisin system in neuroinflammation and neurodegenerative diseases: update and novel perspective
P Pignataro, M Dicarlo, R Zerlotin, C Zecca… - International Journal of …, 2021 - mdpi.com
Irisin, the circulating peptide originating from fibronectin type III domain-containing protein 5
(FNDC5), is mainly expressed by muscle fibers under peroxisome proliferator-activated …
(FNDC5), is mainly expressed by muscle fibers under peroxisome proliferator-activated …
[HTML][HTML] Exerkines and long-term synaptic potentiation: Mechanisms of exercise-induced neuroplasticity
Physical exercise may improve cognitive function by modulating molecular and cellular
mechanisms within the brain. We propose that the facilitation of long-term synaptic …
mechanisms within the brain. We propose that the facilitation of long-term synaptic …