Novel chemotherapy options for advanced thyroid tumors: small molecules offer great hope

HA Deshpande, SN Gettinger… - Current opinion in …, 2008 - journals.lww.com
The recent explosion of targeted agents available for study has generated enthusiasm for
oncologists treating thyroid cancer. Antiangiogenesis strategies in particular appear …

Anaplastic thyroid carcinoma: Failure of conventional therapy but hope of targeted therapy

P Lennon, S Deady, ML Healy, M Toner… - Head & …, 2016 - Wiley Online Library
Background Anaplastic thyroid cancer has a median survival between 1.2 and 10 months.
The purpose of our study was to evaluate the outcomes of patients with anaplastic thyroid …

Anaplastic thyroid cancer, tumorigenesis and therapy

JP O'Neill, D Power, C Condron… - Irish journal of medical …, 2010 - Springer
Background Anaplastic thyroid cancer (ATC) is a fatal endocrine malignancy. Current
therapy fails to significantly improve survival. Recent insights into thyroid tumorigenesis, post …

The role of surgery for anaplastic thyroid carcinoma in the era of targeted therapeutics: A scoping review

EF Cleere, TJ Crotty, JM Hintze… - Laryngoscope …, 2023 - Wiley Online Library
Background Questions exist regarding patient selection for surgery in anaplastic thyroid
carcinoma (ATC), particularly with the advent of neoadjuvant‐targeted therapeutics. The …

[HTML][HTML] Clinical outcome and toxicity in the treatment of anaplastic thyroid cancer in elderly patients

T Augustin, D Oliinyk, VF Koehler, J Rauch… - Journal of Clinical …, 2020 - mdpi.com
Background: The present study aims to evaluate the outcomes and toxicity of elderly
anaplastic thyroid cancer (ATC) patients receiving (chemo) radiotherapy, as well as to …

External beam radiotherapy in thyroid carcinoma: clinical review and recommendations of the AIRO “Radioterapia Metabolica” Group

M Mangoni, C Gobitti, R Autorino, L Cerizza… - Tumori …, 2017 - journals.sagepub.com
The therapeutic approach to thyroid carcinoma usually involves surgery as initial treatment.
The use of external beam radiotherapy (EBRT) is limited to high-risk patients and depends …

Effects of the histone deacetylase inhibitor valproic acid on the sensitivity of anaplastic thyroid cancer cell lines to imatinib

MG Catalano, M Pugliese, R Poli… - Oncology …, 2009 - spandidos-publications.com
New therapeutic approaches are mandatory for anaplastic thyroid cancer. We investigated
the ability of a new combined treatment using valproic acid (VPA), the only clinically …

Old and new insights in the treatment of thyroid carcinoma

JM Gasent Blesa, E Grande Pulido… - Journal of Thyroid …, 2010 - Wiley Online Library
Thyroid cancer is the endocrine tumor that bears the highest incidence with 33 550 new
cases per year. It bears an excellent prognosis with a mortality of 1530 patients per year …

Anaplastic thyroid cancer in young patients: a contemporary review

M Li, M Milas, C Nasr, JA Brainard, MJ Khan… - American journal of …, 2013 - Elsevier
Purpose Little is known about prognostic factors and treatment outcomes in young patients
with anaplastic thyroid cancer (ATC). The goal of this study is to define the clinical features of …

A case of anaplastic thyroid cancer with long-term survival

H Koussis, M Maruzzo, A Scola, EC Ide… - Anticancer …, 2010 - ar.iiarjournals.org
Anaplastic thyroid carcinoma (ATC)(less than 10% of all thyroid cancer) is a high-grade
neoplasm, characterized by an aggressive clinical course and refractoriness to currently …