Health effects of vitamin D supplementation: lessons learned from randomized controlled trials and mendelian randomization studies
R Bouillon, MS LeBoff, RE Neale - Journal of Bone and Mineral …, 2023 - academic.oup.com
Vitamin D plays an important role in calcium homeostasis and many cellular processes.
Although vitamin D supplements are widely recommended for community‐dwelling adults …
Although vitamin D supplements are widely recommended for community‐dwelling adults …
Vitamin D and human health: evidence from Mendelian randomization studies
A Fang, Y Zhao, P Yang, X Zhang… - European Journal of …, 2024 - Springer
We summarized the current evidence on vitamin D and major health outcomes from
Mendelian randomization (MR) studies. PubMed and Embase were searched for original …
Mendelian randomization (MR) studies. PubMed and Embase were searched for original …
[HTML][HTML] Smoking is an independent but not a causal risk factor for moderate to severe psoriasis: a Mendelian randomization study of 105,912 individuals
C Näslund-Koch, S Vedel-Krogh, SE Bojesen… - Frontiers in …, 2023 - frontiersin.org
Background Smoking is strongly associated with higher risk of psoriasis in several
observational studies; however, whether this association is causal or can be explained by …
observational studies; however, whether this association is causal or can be explained by …
The relationship between serum 25-hydroxyvitamin D levels and osteoporosis in postmenopausal women
D Wang, Y Yang - Clinical interventions in aging, 2023 - Taylor & Francis
Background Vitamin D status is indicated by serum 25-hydroxyvitamin D [25 (OH) D] levels,
and the positive effects of high levels of vitamin D on bone mineral density (BMD) have not …
and the positive effects of high levels of vitamin D on bone mineral density (BMD) have not …
[HTML][HTML] Nationwide vitamin D status in older Brazilian adults and its determinants: The Brazilian Longitudinal Study of Aging (ELSI)
MF Lima-Costa, JVM Mambrini… - Scientific reports, 2020 - nature.com
Little is known about vitamin D status in older adults in South America, where exposures to
ultra-violet radiation are high. We examined the distribution of serum 25-hydroxyvitamin D …
ultra-violet radiation are high. We examined the distribution of serum 25-hydroxyvitamin D …
Systematic comparison of Mendelian randomisation studies and randomised controlled trials using electronic databases
MK Sobczyk, J Zheng, GD Smith, TR Gaunt - BMJ open, 2023 - bmjopen.bmj.com
Objective To scope the potential for (semi)-automated triangulation of Mendelian
randomisation (MR) and randomised controlled trials (RCTs) evidence since the two …
randomisation (MR) and randomised controlled trials (RCTs) evidence since the two …
Serum 25 hydroxyvitamin D concentrations in individuals over 80 years old and their correlations with musculoskeletal and health parameters
MZ Foroni, MS Cendoroglo, EN Sakane, RV Marin-Mio… - Endocrine, 2023 - Springer
Purpose The present study aims to evaluate the serum concentrations of 25 hydroxyvitamin
D [25 (OH) D] in individuals aged≥ 80 years, independent, free-living in Sao Paulo, Brazil …
D [25 (OH) D] in individuals aged≥ 80 years, independent, free-living in Sao Paulo, Brazil …
[HTML][HTML] Predisposing factors for a second fragile hip fracture in a population of 1130 patients with hip fractures, treated at Oulu university hospital in 2013–2016: a …
N Helynen, L Rantanen, P Lehenkari… - Archives of Orthopaedic …, 2023 - Springer
Objective The life-time risk of a second fragile hip fracture is 8.4%, but the risk factors that
predispose to a second hip fracture remain unresolved. This study aimed to define risk …
predispose to a second hip fracture remain unresolved. This study aimed to define risk …
Interaction between MARK3 (rs11623869), PLCB4 (rs6086746) and GEMIN2 (rs2277458) variants with bone mineral density and serum 25-hidroxivitamin D levels in …
DI Aparicio-Bautista, RF Jiménez-Ortega… - Frontiers in …, 2024 - frontiersin.org
Introduction Understanding the genetic factors contributing to variations in bone mineral
density (BMD) and vitamin D could provide valuable insights into the pathogenesis of …
density (BMD) and vitamin D could provide valuable insights into the pathogenesis of …
The associations of serum vitamin D and bone turnover markers with the type and severity of hip fractures in older women
J Zhao, Q Cai, D Jiang, L Wang, S Chen… - Clinical Interventions in …, 2020 - Taylor & Francis
Purpose Vitamin D (25 [OH] D) status and bone turnover markers (BTMs) are considered
important determinants of bone quality, which is associated with the risk of hip fractures …
important determinants of bone quality, which is associated with the risk of hip fractures …