Comparative effects of inhaled diesel exhaust and ambient fine particles on inflammation, atherosclerosis, and vascular dysfunction

C Quan, Q Sun, M Lippmann, LC Chen - Inhalation toxicology, 2010 - Taylor & Francis
Ambient air PM2. 5 (particulate matter less than 2.5 μm in diameter) has been associated
with cardiovascular diseases (CVDs), but the underlying mechanisms affecting CVDs are …

Air pollutants disrupt iron homeostasis to impact oxidant generation, biological effects, and tissue injury

AJ Ghio, JM Soukup, LA Dailey, MC Madden - Free Radical Biology and …, 2020 - Elsevier
Air pollutants cause changes in iron homeostasis through: 1) a capacity of the pollutant, or a
metabolite (s), to complex/chelate iron from pivotal sites in the cell or 2) an ability of the …

Direct particle-to-cell deposition of coarse ambient particulate matter increases the production of inflammatory mediators from cultured human airway epithelial cells

J Volckens, L Dailey, G Walters… - Environmental science & …, 2009 - ACS Publications
Exposure of cultured cells to particulate matter air pollution is usually accomplished by
collecting particles on a solid matrix, extracting the particles from the matrix, suspending …

[HTML][HTML] Oxidant-induced epithelial alarmin pathway mediates lung inflammation and functional decline following ultrafine carbon and ozone inhalation co-exposure

N Majumder, WT Goldsmith, VK Kodali, M Velayutham… - Redox Biology, 2021 - Elsevier
Environmental inhalation exposures are inherently mixed (gases and particles), yet
regulations are still based on single toxicant exposures. While the impacts of individual …

Redox regulation of lung inflammation by thioredoxin

T Nakamura, H Nakamura, T Hoshino… - Antioxidants & redox …, 2005 - liebertpub.com
The lungs are the richest in oxygen among the various organs of the body and are always
subject to harmful reactive oxygen species. Regulation of the reduction/oxidation (redox) …

[HTML][HTML] Ozone enhances the airway inflammation initiated by diesel exhaust

J Bosson, J Pourazar, B Forsberg, E Ädelroth… - Respiratory …, 2007 - Elsevier
Exposure to air pollution is associated with adverse health effects, with particulate matter
(PM) and ozone (O3) both indicated to be of considerable importance. Diesel engine …

[PDF][PDF] Health aspects of air pollution with particulate matter, ozone and nitrogen dioxide: report on a WHO working group, Bonn, Germany 13-15 January 2003

World Health Organization - 2003 - apps.who.int
Detailed knowledge on the effects of air pollutants on human health is a prerequisite for the
development of effective policies to reduce the adverse impact of ambient air pollution. The …

Diesel exhaust exposure enhances the ozone-induced airway inflammation in healthy humans

J Bosson, S Barath, J Pourazar… - European …, 2008 - Eur Respiratory Soc
Exposure to particulate matter and ozone cause adverse airway reactions. Individual
pollutant effects are often addressed separately, despite coexisting in ambient air. The …

Effects of air/fuel ratio and ozone aging on physicochemical properties and oxidative potential of soot particles

J Zhu, Y Chen, J Shang, T Zhu - Chemosphere, 2019 - Elsevier
Fuel combustion conditions and atmospheric aging processes can affect the
physicochemical properties of soot particles, which further change the oxidative potential …

Grainyhead-like 2 reverses the metabolic changes induced by the oncogenic epithelial–mesenchymal transition: effects on anoikis

JC Farris, PM Pifer, L Zheng, E Gottlieb, J Denvir… - Molecular Cancer …, 2016 - AACR
Resistance to anoikis is a prerequisite for tumor metastasis. The epithelial-to-mesenchymal
transition (EMT) allows tumor cells to evade anoikis. The wound-healing regulatory …