Comparative effects of inhaled diesel exhaust and ambient fine particles on inflammation, atherosclerosis, and vascular dysfunction
C Quan, Q Sun, M Lippmann, LC Chen - Inhalation toxicology, 2010 - Taylor & Francis
Ambient air PM2. 5 (particulate matter less than 2.5 μm in diameter) has been associated
with cardiovascular diseases (CVDs), but the underlying mechanisms affecting CVDs are …
with cardiovascular diseases (CVDs), but the underlying mechanisms affecting CVDs are …
Air pollutants disrupt iron homeostasis to impact oxidant generation, biological effects, and tissue injury
AJ Ghio, JM Soukup, LA Dailey, MC Madden - Free Radical Biology and …, 2020 - Elsevier
Air pollutants cause changes in iron homeostasis through: 1) a capacity of the pollutant, or a
metabolite (s), to complex/chelate iron from pivotal sites in the cell or 2) an ability of the …
metabolite (s), to complex/chelate iron from pivotal sites in the cell or 2) an ability of the …
Direct particle-to-cell deposition of coarse ambient particulate matter increases the production of inflammatory mediators from cultured human airway epithelial cells
J Volckens, L Dailey, G Walters… - Environmental science & …, 2009 - ACS Publications
Exposure of cultured cells to particulate matter air pollution is usually accomplished by
collecting particles on a solid matrix, extracting the particles from the matrix, suspending …
collecting particles on a solid matrix, extracting the particles from the matrix, suspending …
[HTML][HTML] Oxidant-induced epithelial alarmin pathway mediates lung inflammation and functional decline following ultrafine carbon and ozone inhalation co-exposure
Environmental inhalation exposures are inherently mixed (gases and particles), yet
regulations are still based on single toxicant exposures. While the impacts of individual …
regulations are still based on single toxicant exposures. While the impacts of individual …
Redox regulation of lung inflammation by thioredoxin
T Nakamura, H Nakamura, T Hoshino… - Antioxidants & redox …, 2005 - liebertpub.com
The lungs are the richest in oxygen among the various organs of the body and are always
subject to harmful reactive oxygen species. Regulation of the reduction/oxidation (redox) …
subject to harmful reactive oxygen species. Regulation of the reduction/oxidation (redox) …
[HTML][HTML] Ozone enhances the airway inflammation initiated by diesel exhaust
J Bosson, J Pourazar, B Forsberg, E Ädelroth… - Respiratory …, 2007 - Elsevier
Exposure to air pollution is associated with adverse health effects, with particulate matter
(PM) and ozone (O3) both indicated to be of considerable importance. Diesel engine …
(PM) and ozone (O3) both indicated to be of considerable importance. Diesel engine …
[PDF][PDF] Health aspects of air pollution with particulate matter, ozone and nitrogen dioxide: report on a WHO working group, Bonn, Germany 13-15 January 2003
World Health Organization - 2003 - apps.who.int
Detailed knowledge on the effects of air pollutants on human health is a prerequisite for the
development of effective policies to reduce the adverse impact of ambient air pollution. The …
development of effective policies to reduce the adverse impact of ambient air pollution. The …
Diesel exhaust exposure enhances the ozone-induced airway inflammation in healthy humans
J Bosson, S Barath, J Pourazar… - European …, 2008 - Eur Respiratory Soc
Exposure to particulate matter and ozone cause adverse airway reactions. Individual
pollutant effects are often addressed separately, despite coexisting in ambient air. The …
pollutant effects are often addressed separately, despite coexisting in ambient air. The …
Effects of air/fuel ratio and ozone aging on physicochemical properties and oxidative potential of soot particles
Fuel combustion conditions and atmospheric aging processes can affect the
physicochemical properties of soot particles, which further change the oxidative potential …
physicochemical properties of soot particles, which further change the oxidative potential …
Grainyhead-like 2 reverses the metabolic changes induced by the oncogenic epithelial–mesenchymal transition: effects on anoikis
Resistance to anoikis is a prerequisite for tumor metastasis. The epithelial-to-mesenchymal
transition (EMT) allows tumor cells to evade anoikis. The wound-healing regulatory …
transition (EMT) allows tumor cells to evade anoikis. The wound-healing regulatory …