Parkinson's disease (PD) is the second most important age-related neurodegenerative
disorder in developed societies, after Alzheimer's disease, with a prevalence ranging from …

Symptoms of Parkinson's disease have been controlled with levodopa for many years;
however, motor complications consisting of wearing off of medication effect and dyskinesias …

New neurons are generated throughout adulthood in two regions of the brain, the olfactory
bulb and dentate gyrus of the hippocampus, and are incorporated into the hippocampal …

Background: Parkinson's disease (PD) is the second commonest neurodegenerative
disease. The genetic basis of PD is indisputable. Both ADORA2A rs5760423 and CYP1A2 …

Abstract Neurodegenerative disorders (NDDs)(Alzheimer's disease, Parkinson's disease)
represent major problems of health in developed countries, with important psychosocial …

Parkinson's disease (PD) is a complex neurodegenerative disorder characterized by a
progressive loss of dopamine neurons of the central nervous system. The disease …

Molecular mechanisms of Parkinson's disease (PD) have already been investigated in
various different omics landscapes. We reviewed the literature about different omics …

Background: Deep brain stimulation (DBS) of the subthalamic nucleus (STN) or globus
pallidus internus (GPi) have been proven to be equally effective in improving motor …

Introduction Levodopa-induced dyskinesia frequently complicates long-term Parkinson's
disease. More in-depth knowledge regarding the role of genetic factors in dyskinesia …

ABSTRACT Introduction Neuropsychiatric disorders (NPDs)(neurodevelopmental, mental,
neurodegenerative, neurotoxic, complex disorders) are the third major problem of health in …