The role of host cytoskeleton in flavivirus infection

Y Zhang, W Gao, J Li, W Wu, Y Jiu - Virologica Sinica, 2019 - Springer
The family of flaviviruses is one of the most medically important groups of emerging
arthropod-borne viruses. Host cell cytoskeletons have been reported to have close contact …

Viral-immune cell interactions at the maternal-fetal interface in human pregnancy

EL Parker, RB Silverstein, S Verma… - Frontiers in …, 2020 - frontiersin.org
The human decidua and placenta form a distinct environment distinguished for its promotion
of immunotolerance to infiltrating semiallogeneic trophoblast cells to enable successful …

Current progress on host antiviral factor IFITMs

L Ren, S Du, W Xu, T Li, S Wu, N Jin, C Li - Frontiers in Immunology, 2020 - frontiersin.org
Host antiviral factor interferon-induced transmembrane proteins (IFITMs) are a kind of small-
molecule transmembrane proteins induced by interferon. Their broad-spectrum antiviral …

Interactome of SARS-CoV-2 modulated host proteins with computationally predicted PPIs: insights from translational systems biology studies

KB Karunakaran, N Balakrishnan… - Frontiers in Systems …, 2022 - frontiersin.org
Accelerated efforts to identify intervention strategies for the COVID-19 pandemic caused by
SARS-CoV-2 need to be supported by deeper investigations into host invasion and …

[PDF][PDF] A vaccine candidate of Zika virus (ZIKV) from polyvalent conserved b-cell epitope on viral glycoprotein: in silico approach.

VD Kharisma, N Widodo… - … & Cellular Archives, 2020 - researchgate.net
Zika virus (ZIKV) is a member of the Flaviviridaefamily. This virus is spread and carried by
mosquitoes (Aedes aegyptiand Aedes albopictus). ZIKV belongs to the Flavivirusgenus …

IFITM3 mediates inflammation induced myocardial injury through JAK2/STAT3 signaling pathway

C Xiong, B Li, R Song, Z Ma, SA Huber, W Liu - Molecular Immunology, 2024 - Elsevier
Myocarditis is an inflammation of the heart muscle often associated with viral infections and
can lead to dilated cardiomyopathy. Interferon-induced transmembrane protein 3 (IFITM3) is …

[HTML][HTML] Interactome of SARS-CoV-2/nCoV19 modulated host proteins with computationally predicted PPIs

KB Karunakaran, N Balakrishnan… - Research …, 2020 - ncbi.nlm.nih.gov
World over, people are looking for solutions to tackle the pandemic coronavirus disease
(COVID-19) caused by the virus SARS-CoV-2/nCoV-19. Notable contributions in biomedical …

In silico predictions of protein interactions between Zika virus and human host

JLLP Pitta, CR dos Santos Vasconcelos… - PeerJ, 2021 - peerj.com
Background The ZIKA virus (ZIKV) belongs to the Flaviviridae family, was first isolated in the
1940s, and remained underreported until its global threat in 2016, where drastic …

Novel Protein–Protein Interactions Highlighting the Crosstalk between Hypoplastic Left Heart Syndrome, Ciliopathies and Neurodevelopmental Delays

KB Karunakaran, GC Gabriel, N Balakrishnan, CW Lo… - Genes, 2022 - mdpi.com
Hypoplastic left heart syndrome (HLHS) is a severe congenital heart disease (CHD)
affecting 1 in 5000 newborns. We constructed the interactome of 74 HLHS-associated genes …

Malignant peritoneal mesothelioma interactome with 417 novel protein–protein interactions

KB Karunakaran, MK Ganapathiraju - BJC Reports, 2024 - nature.com
Abstract Background Malignant peritoneal mesothelioma (MPeM) is an aggressive cancer
affecting the abdominal peritoneal lining and intra-abdominal organs, with a median survival …