[HTML][HTML] Oral delivery of therapeutic peptides and proteins: Technology landscape of lipid-based nanocarriers
S Haddadzadegan, F Dorkoosh… - Advanced drug delivery …, 2022 - Elsevier
The oral administration of therapeutic peptides and proteins is favoured from a patient and
commercial point of view. In order to reach the systemic circulation after oral administration …
commercial point of view. In order to reach the systemic circulation after oral administration …
[HTML][HTML] Liposomes for enhanced bioavailability of water-insoluble drugs: In vivo evidence and recent approaches
MK Lee - Pharmaceutics, 2020 - mdpi.com
It has been known that a considerable number of drugs in clinical use or under development
are water-insoluble drugs with poor bioavailability (BA). The liposomal delivery system has …
are water-insoluble drugs with poor bioavailability (BA). The liposomal delivery system has …
Nanoparticles for oral delivery: Design, evaluation and state-of-the-art
The oral route is a preferred method of drug administration, though achieving effective drug
delivery and minimizing off-target side effects is often challenging. Formulation into …
delivery and minimizing off-target side effects is often challenging. Formulation into …
[HTML][HTML] An update on oral drug delivery via intestinal lymphatic transport
Orally administered drug entities have to survive the harsh gastrointestinal environment,
penetrate the enteric epithelia and circumvent hepatic metabolism before reaching the …
penetrate the enteric epithelia and circumvent hepatic metabolism before reaching the …
[HTML][HTML] Recent advances in oral delivery of drugs and bioactive natural products using solid lipid nanoparticles as the carriers
Chemical and enzymatic barriers in the gastrointestinal (GI) tract hamper the oral delivery of
many labile drugs. The GI epithelium also contributes to poor permeability for numerous …
many labile drugs. The GI epithelium also contributes to poor permeability for numerous …
Advancement in solubilization approaches: a step towards bioavailability enhancement of poorly soluble drugs
L Kumari, Y Choudhari, P Patel, GD Gupta, D Singh… - Life, 2023 - mdpi.com
A drug's aqueous solubility is defined as the ability to dissolve in a particular solvent, and it
is currently a major hurdle in bringing new drug molecules to the market. According to some …
is currently a major hurdle in bringing new drug molecules to the market. According to some …
The influence of nanoparticle properties on oral bioavailability of drugs
Y Wang, C Pi, X Feng, Y Hou, L Zhao… - International journal of …, 2020 - Taylor & Francis
Oral administration has been the most common therapeutic regimen in various diseases
because of its high safety, convenience, lower costs, and high compliance of patients …
because of its high safety, convenience, lower costs, and high compliance of patients …
Solid lipid nanoparticles for enhanced oral absorption: A review
E Salah, MM Abouelfetouh, Y Pan, D Chen… - colloids and surfaces B …, 2020 - Elsevier
Recent trends in nanoparticles-based oral therapy have led to a proliferation of studies to
enhance solubility, permeability and chemical stability of many drugs. One of the significant …
enhance solubility, permeability and chemical stability of many drugs. One of the significant …
Nanoparticle delivery systems in the treatment of diabetes complications
EB Souto, SB Souto, JR Campos, P Severino… - Molecules, 2019 - mdpi.com
Diabetes mellitus, an incurable metabolic disease, is characterized by changes in the
homeostasis of blood sugar levels, being the subcutaneous injection of insulin the first line …
homeostasis of blood sugar levels, being the subcutaneous injection of insulin the first line …
Chitosan-coated nanostructured lipid carriers for transdermal delivery of tetrahydrocurcumin for breast cancer therapy
TH Truong, KP Alcantara, BPI Bulatao… - Carbohydrate …, 2022 - Elsevier
Chitosan (Ch)-coated nanostructured lipid carriers (NLCs) have great potential for
transdermal delivery with high localization of chemotherapeutics in breast cancer. This study …
transdermal delivery with high localization of chemotherapeutics in breast cancer. This study …