Obesity and adverse breast cancer risk and outcome: Mechanistic insights and strategies for intervention

M Picon‐Ruiz, C Morata‐Tarifa… - CA: a cancer journal …, 2017 - Wiley Online Library
Answer questions and earn CME/CNE Recent decades have seen an unprecedented rise in
obesity, and the health impact thereof is increasingly evident. In 2014, worldwide, more than …

[HTML][HTML] Advances in the prevention and treatment of obesity-driven effects in breast cancers

K Chen, J Zhang, NM Beeraka, C Tang… - Frontiers in …, 2022 - frontiersin.org
Obesity and associated chronic inflammation were shown to facilitate breast cancer (BC)
growth and metastasis. Leptin, adiponectin, estrogen, and several pro-inflammatory …

[HTML][HTML] Obesity and breast cancer: a paradoxical and controversial relationship influenced by menopausal status

L García-Estévez, J Cortés, S Pérez, I Calvo… - Frontiers in …, 2021 - frontiersin.org
Breast cancer is the most common tumor in women worldwide, and an increasing public
health concern. Knowledge of both protective and negative risk factors is essential for a …

[HTML][HTML] Inflammation-induced tumorigenesis and metastasis

S Hibino, T Kawazoe, H Kasahara, S Itoh… - International journal of …, 2021 - mdpi.com
Inflammation, especially chronic inflammation, plays a pivotal role in tumorigenesis and
metastasis through various mechanisms and is now recognized as a hallmark of cancer and …

[HTML][HTML] Obesity and breast cancer: role of leptin

F Sánchez-Jiménez, A Pérez-Pérez… - Frontiers in …, 2019 - frontiersin.org
Obesity-related breast cancer is an important threat that affects especially post-menopausal
women. The link between obesity and breast cancer seems to be relying on the …

[HTML][HTML] Biological Properties and Bioactive Components of Allium cepa L.: Focus on Potential Benefits in the Treatment of Obesity and Related Comorbidities

M Marrelli, V Amodeo, G Statti, F Conforti - Molecules, 2018 - mdpi.com
Common onion (Allium cepa L.) is one of the oldest cultivated plants, utilized worldwide as
both vegetable and flavouring. This species is known to contain sulphur amino acids …

[HTML][HTML] Obesity, leptin and breast cancer: epidemiological evidence and proposed mechanisms

S Andò, L Gelsomino, S Panza, C Giordano… - Cancers, 2019 - mdpi.com
The prevalence of obesity has been steadily increasing over the past few decades in several
developed and developing countries, with resultant hazardous health implications …

[HTML][HTML] Updating the role of obesity and cholesterol in breast cancer

L Garcia-Estevez, G Moreno-Bueno - Breast Cancer Research, 2019 - Springer
Background Breast cancer is the second most common cause of cancer-related death
among women. Advances in our understanding of the disease have translated into better …

The weight of obesity in breast cancer progression and metastasis: Clinical and molecular perspectives

I Barone, C Giordano, D Bonofiglio, S Ando… - Seminars in cancer …, 2020 - Elsevier
The escalating epidemic of overweight and obesity is currently recognized as one of the
most significant health and economic concern worldwide. At the present time, over 1.9 billion …

[HTML][HTML] Leptin: A heavyweight player in obesity-related cancers

A Caruso, L Gelsomino, S Panza, FM Accattatis… - Biomolecules, 2023 - mdpi.com
Obesity, defined as the abnormal or excessive expansion of white adipose tissue, has
reached pandemic proportions and is recognized as an important health concern since it is …