[HTML][HTML] The role of Insulin-like growth factor 2 mRNA-binding proteins (IGF2BPs) as m6A readers in cancer
CY Sun, D Cao, BB Du, CW Chen… - International Journal of …, 2022 - ncbi.nlm.nih.gov
RNA can be modified by over 170 types of distinct chemical modifications, and the most
abundant internal modification of mRNA in eukaryotes is N6-methyladenosine (m 6 A). The …
abundant internal modification of mRNA in eukaryotes is N6-methyladenosine (m 6 A). The …
[HTML][HTML] Cancer metastasis under the magnifying glass of epigenetics and epitranscriptomics
Most of the cancer-associated mortality and morbidity can be attributed to metastasis. The
role of epigenetic and epitranscriptomic alterations in cancer origin and progression has …
role of epigenetic and epitranscriptomic alterations in cancer origin and progression has …
DeepSTF: predicting transcription factor binding sites by interpretable deep neural networks combining sequence and shape
P Ding, Y Wang, X Zhang, X Gao, G Liu… - Briefings in …, 2023 - academic.oup.com
Precise targeting of transcription factor binding sites (TFBSs) is essential to comprehending
transcriptional regulatory processes and investigating cellular function. Although several …
transcriptional regulatory processes and investigating cellular function. Although several …
[HTML][HTML] DARS2 overexpression is associated with PET/CT metabolic parameters and affects glycolytic activity in lung adenocarcinoma
XS Liu, LL Yuan, Y Gao, X Ming, YH Zhang… - Journal of Translational …, 2023 - Springer
Background This study investigated the correlation between the expression of DARS2 and
metabolic parameters of 18F-FDG PET/CT, and explored the potential mechanisms of …
metabolic parameters of 18F-FDG PET/CT, and explored the potential mechanisms of …
[HTML][HTML] Comprehensive analysis of ZNF family genes in prognosis, immunity, and treatment of esophageal cancer
K Hong, Q Yang, H Yin, N Wei, W Wang, B Yu - BMC cancer, 2023 - Springer
Background As a common malignant tumor, esophageal carcinoma (ESCA) has a low early
diagnosis rate and poor prognosis. This study aimed to construct the prognostic features …
diagnosis rate and poor prognosis. This study aimed to construct the prognostic features …
[HTML][HTML] DARS2 is a prognostic biomarker and correlated with immune infiltrates and cuproptosis in lung adenocarcinoma
XS Liu, J Zeng, YH Zhang, Y Zhang, Y Gao… - American journal of …, 2023 - ncbi.nlm.nih.gov
Overexpression of DARS2 may enhance the progression of hepatocellular carcinoma
(HCC). However, there are few extensive reports on DARS2 function in lung …
(HCC). However, there are few extensive reports on DARS2 function in lung …
[HTML][HTML] Role of RBMS3 novel potential regulator of the EMT phenomenon in physiological and pathological processes
T Górnicki, J Lambrinow, M Mrozowska… - International journal of …, 2022 - mdpi.com
RNA-binding protein 3 (RBMS3) plays a significant role in embryonic development and the
pathogenesis of many diseases, especially cancer initiation and progression. The multiple …
pathogenesis of many diseases, especially cancer initiation and progression. The multiple …
[HTML][HTML] Cisplatin-induced increase in heregulin 1 and its attenuation by the monoclonal ErbB3 antibody seribantumab in bladder cancer
TM Steele, MM Tsamouri, S Siddiqui, CA Lucchesi… - Scientific reports, 2023 - nature.com
Cisplatin-based combination chemotherapy is the foundation for treatment of advanced
bladder cancer (BlCa), but many patients develop chemoresistance mediated by increased …
bladder cancer (BlCa), but many patients develop chemoresistance mediated by increased …
New candidates in the differential diagnosis of malignant mesothelioma from benign mesothelial hyperplasia and adenocarcinoma; DARS2 and suprabasin
O Ucer, N Kocaman - Tissue and Cell, 2022 - Elsevier
Objectives Malignant mesothelioma (MM) is a primary malignant tumour with a very bad
prognosis, which develops from the mesothelial cells lining the serosal surfaces. Because …
prognosis, which develops from the mesothelial cells lining the serosal surfaces. Because …
[HTML][HTML] Assessment of genetic susceptibility to multiple primary cancers through whole-exome sequencing in two large multi-ancestry studies
Background Up to one of every six individuals diagnosed with one cancer will be diagnosed
with a second primary cancer in their lifetime. Genetic factors contributing to the …
with a second primary cancer in their lifetime. Genetic factors contributing to the …