Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 and CYP2C19 Genotypes and Dosing of Selective Serotonin Reuptake …
Selective serotonin reuptake inhibitors (SSRIs) are primary treatment options for major
depressive and anxiety disorders. CYP2D6 and CYP2C19 polymorphisms can influence the …
depressive and anxiety disorders. CYP2D6 and CYP2C19 polymorphisms can influence the …
Review and consensus on pharmacogenomic testing in psychiatry
The implementation of pharmacogenomic (PGx) testing in psychiatry remains modest, in part
due to divergent perceptions of the quality and completeness of the evidence base and …
due to divergent perceptions of the quality and completeness of the evidence base and …
Pharmacogenetic allele nomenclature: International workgroup recommendations for test result reporting
LV Kalman, JAG Agúndez, ML Appell… - Clinical …, 2016 - Wiley Online Library
This article provides nomenclature recommendations developed by an international
workgroup to increase transparency and standardization of pharmacogenetic (PGx) result …
workgroup to increase transparency and standardization of pharmacogenetic (PGx) result …
Effectiveness of pharmacogenomic tests including CYP2D6 and CYP2C19 genomic variants for guiding the treatment of depressive disorders: systematic review and …
Major depressive disorders are prevalent conditions with limited treatment response and
remission. Pharmacogenomics tests including CYP2D6 and CYP2C19 genomic variants …
remission. Pharmacogenomics tests including CYP2D6 and CYP2C19 genomic variants …
[HTML][HTML] Pharmacogenomics: A road ahead for precision medicine in psychiatry
Psychiatric genomics is providing insights into the nature of psychiatric conditions that in
time should identify new drug targets and improve patient care. Less attention has been paid …
time should identify new drug targets and improve patient care. Less attention has been paid …
Constellation: a tool for rapid, automated phenotype assignment of a highly polymorphic pharmacogene, CYP2D6, from whole-genome sequences
An important component of precision medicine—the use of whole-genome sequencing
(WGS) to guide lifelong healthcare—is electronic decision support to inform drug choice and …
(WGS) to guide lifelong healthcare—is electronic decision support to inform drug choice and …
Genetic variants in major depressive disorder: from pathophysiology to therapy
In spite of promising preclinical results there is a decreasing number of new registered
medications in major depression. The main reason behind this fact is the lack of confirmation …
medications in major depression. The main reason behind this fact is the lack of confirmation …
Implementation of clinical pharmacogenomics within a large health system: from electronic health record decision support to consultation services
JK Hicks, D Stowe, MA Willner, M Wai… - … : The Journal of …, 2016 - Wiley Online Library
The number of clinically relevant gene‐based guidelines and recommendations pertaining
to drug prescribing continues to grow. Incorporating gene–drug interaction information into …
to drug prescribing continues to grow. Incorporating gene–drug interaction information into …
Pharmacogenetics of antipsychotics
EJ Brandl, JL Kennedy… - The Canadian Journal of …, 2014 - journals.sagepub.com
Objective: During the past decades, increasing efforts have been invested in studies to
unravel the influence of genetic factors on antipsychotic (AP) dosage, treatment response …
unravel the influence of genetic factors on antipsychotic (AP) dosage, treatment response …
The role of genetics and genomics in clinical psychiatry
MR Hoehe, DJ Morris-Rosendahl - Dialogues in clinical …, 2018 - Taylor & Francis
The enormous successes in the genetics and genomics of many diseases have provided the
basis for the advancement of precision medicine. Thus, the detection of genetic variants …
basis for the advancement of precision medicine. Thus, the detection of genetic variants …