Zebrafish as a model to study beta-cell development and regeneration

MC Toselli - 2020 - open.library.ubc.ca
Diabetes is characterized by insufficient amounts of insulin, a hormone produced by the beta-
cells in the pancreatic islets. While current treatment options such as insulin injections …

[PDF][PDF] Роль регуляторных мастер генов в развитии рака поджелудочной железы

ИП Чернов - ibch.ru
Опухолевые заболевания являются одной из основных причин смерти в мире и
представляют собой наиболее серьезную проблему медицины. По данным ВОЗ в 2018 …

[PDF][PDF] The Organization, Structure, and Role of Endothelial Cells During Organogenesis

E Daniel - 2019 - utswmed-ir.tdl.org
Cellular crosstalk is essential for proper organogenesis. Although originally assumed to be
simple conduits for blood, endothelial cells (ECs) actively coordinate organ development …

Recreation of pancreatic niche allows for novel methods for human, mature beta derivation from pluripotent stem cells

M Borowiak, J Chmielowiec, Y Diane - 2018 - Google Patents
Embodiments of the disclosure concern methods and compositions related to treatment of
diabetes and/or related conditions using cell therapy. In specific embodiments, cells that …

[图书][B] Comprehensive Functional and Transcriptional Analysis of Human Pancreatic Islets from Controls and Individuals with Type 1 Diabetes (T1D)

S Shrestha - 2018 - search.proquest.com
Type 1 Diabetes is chronic disease where immune moderated destruction of insulin
producing β cells disrupts normal glucose homeostasis in the body. Recent findings show …

Systems Biology: Salivary Gland Development, Disease, and Regenerative Medicine

M Larsen, P Bogdanov, R Sood, HR Kwon… - … Gland Development and …, 2017 - Springer
There are multiple challenges currently facing clinical salivary gland research,
encompassing a wide range of topics from understanding development to understanding …

The Situation Is More Complex Than Anticipated

A Bikfalvi, A Bikfalvi - A Brief History of Blood and Lymphatic Vessels, 2017 - Springer
Vessels are not uniform tubes but are subdivided into arterial, venous, and lymphatic
vessels. Large vessels (arteries, veins, large lymphatic trunks), medium-size vessels …

Dissecting Genes and Signals Controlling Pancreatic Islet Morphogenesis and Differentiation

PT Pauerstein - 2017 - search.proquest.com
The pancreas is a mixed endocrine and exocrine organ associated with the digestive tract.
Pancreatic islets are spheroid endocrine micro-organs dispersed throughout the pancreas …

Investigation into the function of endothelial cells and their signaling in early salivary gland development

HR Kwon - 2016 - scholarsarchive.library.albany.edu
Functional vasculature regulates organ formation and regeneration. Perfusion-independent
and nutrition-independent endothelial regulation of epithelial patterning is of considerable …

[图书][B] The roles of pancreatic hormones in regulating pancreas development and beta cell regeneration

L Ye - 2015 - search.proquest.com
Diabetes mellitus is a group of related metabolic diseases that share a common pathological
mechanism: insufficient insulin signaling. Insulin is a hormone secreted from pancreatic β …