The interplay between the renin-angiotensin-aldosterone system and parathyroid hormone

MH Zheng, FXZ Li, F Xu, X Lin, Y Wang… - Frontiers in …, 2020 - frontiersin.org
The renin-angiotensin-aldosterone system (RAAS) is the regulatory system by which renin
induces aldosterone production. Angiotensin II (Ang II) is the main effector substance of the …

Bone and mineral metabolism in patients with primary aldosteronism: A systematic review and meta-analysis

A Wang, Y Wang, H Liu, X Hu, J Li, H Xu… - Frontiers in …, 2022 - frontiersin.org
Purpose Patients with primary aldosteronism (PA) tend to exhibit a high prevalence of
osteoporosis (OP) that may vary by whether PA is unilateral or bilateral, and responsive to …

Higher risk of chronic kidney disease and progressive kidney function impairment in primary aldosteronism than in essential hypertension. Case-control study

M Fernández-Argüeso, E Pascual-Corrales… - Endocrine, 2021 - Springer
Purpose To study the differences in the prevalence, risk, and grade of control of different
cardiometabolic comorbidities in patients with primary aldosteronism (PA) and essential …

Cross-disciplinary approach of adrenal tumors: insights into primary aldosteronism-related mineral metabolism status and osteoporotic fracture risk

AI Trandafir, AM Gheorghe, OC Sima, A Ciuche… - International Journal of …, 2023 - mdpi.com
Our objective was to overview the novel aspects in the field of adrenal gland neoplasms,
namely, the management of bone status with respect to primary aldosteronism (PA). In the …

The crosstalk between aldosterone and calcium metabolism in primary aldosteronism: A possible calcium metabolism-associated aberrant “neoplastic” …

X Gao, Y Yamazaki, Y Tezuka, Y Onodera… - The Journal of Steroid …, 2019 - Elsevier
Intracellular calcium (Ca) levels play pivotal roles in aldosterone biosynthesis. Several
somatic mutations of ion channels associated with aldosterone over-production were …

The Relationship between Renin–Angiotensin–Aldosterone System (RAAS) Activity, Osteoporosis and Estrogen Deficiency in Type 2 Diabetes

BC Mkhize, P Mosili, PS Ngubane, NH Sibiya… - International Journal of …, 2023 - mdpi.com
Type 2 diabetes (T2D) is associated with a plethora of comorbidities, including osteoporosis,
which occurs due to an imbalance between bone resorption and formation. Numerous …

Primary and secondary hyperparathyroidism in patients with primary aldosteronism–findings from the German Conn's registry

E Asbach, M Bekeran, A König, K Lang… - Experimental and …, 2020 - thieme-connect.com
Context Recent studies support a bidirectional interaction between aldosterone and
parathyroid hormone (PTH), possibly increasing the individual cardiovascular risk. Primary …

Parathyroid hormone and phosphate homeostasis in patients with Bartter and Gitelman syndrome: an international cross-sectional study

MFA Verploegen, R Vargas-Poussou… - Nephrology dialysis …, 2022 - academic.oup.com
Background Small cohort studies have reported high parathyroid hormone (PTH) levels in
patients with Bartter syndrome and lower serum phosphate levels have anecdotally been …

Disentangling the relationships between the renin–angiotensin–aldosterone system, calcium physiology, and risk for kidney stones

O Bayomy, S Zaheer, JS Williams… - The Journal of …, 2020 - academic.oup.com
Context Complex relationships between aldosterone and calcium homeostasis have been
proposed. Objective To disentangle the influence of aldosterone and intravascular volume …

Cardiovascular consequences of parathyroid disorders in adults

J Bollerslev, E Sjöstedt, L Rejnmark - Annales d'endocrinologie, 2021 - Elsevier
PTH is a metabolic active hormone primarily regulating calcium and phosphate homeostasis
in a very tight and short term-manner. Parathyroid disorders in adult patients reflect a variety …