[HTML][HTML] Dominant negative effect of a truncated erythropoietin receptor (EPOR-T) on erythropoietin-induced erythroid differentiation: possible involvement of EPOR-T …
R Shimizu, N Komatsu, Y Miura - Experimental hematology, 1999 - Elsevier
We isolated a human leukemic cell line UT-7/GM from UT-7, which can differentiate into
mature erythroid cells with erythropoietin (EPO) treatment. Using this cell line, we examined …
mature erythroid cells with erythropoietin (EPO) treatment. Using this cell line, we examined …
[PDF][PDF] Transient noise amplification and gene expression synchronization in a bistable mammalian cell-fate switch
S Palani, CA Sarkar - Cell reports, 2012 - cell.com
Progenitor cells within a clonal population show variable proclivity toward lineage
commitment and differentiation. This cell-to-cell variability has been attributed to …
commitment and differentiation. This cell-to-cell variability has been attributed to …
TEL/ETV6 accelerates erythroid differentiation and inhibits megakaryocytic maturation in a human leukemia cell line UT‐7/GM
W Takahashi, K Sasaki, N Komatsu, K Mitani - Cancer science, 2005 - Wiley Online Library
TEL/ETV6 accelerates erythroid differentiation in the murine erythroleukemia cell line. To
clarify the effects of TEL on megakaryocytic maturation as well as erythroid differentiation …
clarify the effects of TEL on megakaryocytic maturation as well as erythroid differentiation …
Terminal megakaryocytic differentiation of TF-1 cells is induced by phorbol esters and thrombopoietin and is blocked by expression of PML/RARα fusion protein
U Testa, F Grignani, HJ Hassan, D Rogaia, R Masciulli… - Leukemia, 1998 - nature.com
We have analyzed the differentiation program of growth factor-dependent TF-1
erythroleukemia cells as well as clones with inducible expression of the APL-specific …
erythroleukemia cells as well as clones with inducible expression of the APL-specific …
Developmental expression of plasminogen activator inhibitor-1 associated with thrombopoietin-dependent megakaryocytic differentiation
S Madoiwa, N Komatsu, J Mimuro… - Blood, The Journal …, 1999 - ashpublications.org
Abstract Plasminogen activator inhibitor-1 (PAI-1) is present in the platelet-granule and is
released on activation. However, there is some debate as to whether the megakaryocyte …
released on activation. However, there is some debate as to whether the megakaryocyte …
A common signaling pathway is activated in erythroid cells expressing high levels of fetal hemoglobin: a potential role for cAMP-elevating agents in β-globin disorders
T Ikuta, Y Kuroyanagi, N Odo, S Liu - Journal of blood medicine, 2013 - Taylor & Francis
Background Although erythroid cells prepared from fetal liver, cord blood, or blood from β-
thalassemia patients are known to express fetal hemoglobin at high levels, the underlying …
thalassemia patients are known to express fetal hemoglobin at high levels, the underlying …
Regulation of both erythroid and megakaryocytic differentiation of a human leukemia cell line, UT-7
Y Miura, K Kirito, N Komatsu - Acta haematologica, 1998 - karger.com
UT-7 is a human megakaryoblastic leukemia cell line with absolute dependence on
interleukin-3, granulocyte-macrophage colony-stimulating factor (GM-CSF), or erythropoietin …
interleukin-3, granulocyte-macrophage colony-stimulating factor (GM-CSF), or erythropoietin …
RUNX1 suppression induces megakaryocytic differentiation of UT-7/GM cells
R Nagai, E Matsuura, Y Hoshika, E Nakata… - Biochemical and …, 2006 - Elsevier
The transcription factor RUNX1 plays a crucial role in hematopoiesis. RUNX1 regulates both
differentiation and proliferation of hematopoietic cells. Several reports have shown that …
differentiation and proliferation of hematopoietic cells. Several reports have shown that …
Systemic Optimization of Gene Electrotransfer Protocol Using Hard-to-Transfect UT-7 Cell Line as a Model
R Vadeikienė, B Jakštys, R Ugenskienė, S Šatkauskas… - Biomedicines, 2022 - mdpi.com
Non-adherent cells are difficult to transfect with chemical-mediated delivery methods.
Electroporation is an attractive strategy to transfer the molecules of interest into suspension …
Electroporation is an attractive strategy to transfer the molecules of interest into suspension …
Robust hematopoietic progenitor cell commitment in the presence of a conflicting cue
Hematopoietic lineage commitment is regulated by cytokines and master transcription
factors, but it remains unclear how a progenitor cell chooses a lineage in the face of …
factors, but it remains unclear how a progenitor cell chooses a lineage in the face of …