[HTML][HTML] Health benefits and side effects of short-chain fatty acids

RG Xiong, DD Zhou, SX Wu, SY Huang, A Saimaiti… - Foods, 2022 - mdpi.com
The gut microbiota and their metabolites could play an important role in health and diseases
of human beings. Short-chain fatty acids (SCFAs) are mainly produced by gut microbiome …

[HTML][HTML] Cardiotoxicity of anticancer drugs: Molecular mechanisms and strategies for cardioprotection

MB Morelli, C Bongiovanni, S Da Pra… - Frontiers in …, 2022 - frontiersin.org
Chemotherapy and targeted therapies have significantly improved the prognosis of
oncology patients. However, these antineoplastic treatments may also induce adverse …

Short‐chain fatty acids regulate B cells differentiation via the FFA2 receptor to alleviate rheumatoid arthritis

Y Yao, X Cai, Y Zheng, M Zhang, W Fei… - British Journal of …, 2022 - Wiley Online Library
Background and Purpose Short‐chain fatty acids (SCFAs) are metabolites from gut microbes
involved in the host's inflammatory response and immunity. The aim of this study was to …

[HTML][HTML] Cardiomyocyte senescence and cellular communications within myocardial microenvironments

X Tang, PH Li, HZ Chen - Frontiers in endocrinology, 2020 - frontiersin.org
Cardiovascular diseases have become the leading cause of human death. Aging is an
independent risk factor for cardiovascular diseases. Cardiac aging is associated with …

Protein posttranslational modifications in health and diseases: Functions, regulatory mechanisms, and therapeutic implications

Q Zhong, X Xiao, Y Qiu, Z Xu, C Chen, B Chong… - MedComm, 2023 - Wiley Online Library
Protein posttranslational modifications (PTMs) refer to the breaking or generation of covalent
bonds on the backbones or amino acid side chains of proteins and expand the diversity of …

[HTML][HTML] The role of short-chain fatty acids of gut microbiota origin in hypertension

Y Wu, H Xu, X Tu, Z Gao - Frontiers in Microbiology, 2021 - frontiersin.org
Hypertension is a significant risk factor for cardiovascular and cerebrovascular diseases,
and its development involves multiple mechanisms. Gut microbiota has been reported to be …

Gut microbiota-derived short-chain fatty acids facilitate microbiota: host cross talk and modulate obesity and hypertension

HB Overby, JF Ferguson - Current hypertension reports, 2021 - Springer
Abstract Purpose of Review The purpose of this review is to summarize the evidence
supporting a role of short-chain fatty acids (SCFAs) as messengers facilitating cross talk …

[HTML][HTML] Function and mechanism of histone β-hydroxybutyrylation in health and disease

T Zhou, X Cheng, Y He, Y Xie, F Xu, Y Xu… - Frontiers in …, 2022 - frontiersin.org
Histone post-translational modifications (HPTMs) are essential epigenetic mechanisms that
affect chromatin-associated nuclear processes without altering the DNA sequence. With the …

[HTML][HTML] Research progress on post-translational modification of proteins and cardiovascular diseases

XL Cheng, K Wang, Y Zhao, K Wang - Cell Death Discovery, 2023 - nature.com
Cardiovascular diseases (CVDs) such as atherosclerosis, myocardial remodeling,
myocardial ischemia-reperfusion (I/R) injury, heart failure, and oxidative stress are among …

[HTML][HTML] Gut microbiota and atherosclerosis—focusing on the plaque stability

X Shen, L Li, Z Sun, G Zang, L Zhang… - Frontiers in …, 2021 - frontiersin.org
Cardiovascular diseases (CVDs) are major causes of mortality and morbidity in the modern
society. The rupture of atherosclerotic plaque can induce thrombus formation, which is the …