Over the past decades, a multitude of experimental drugs have been shown to delay
disease progression in preclinical animal models of amyotrophic lateral sclerosis (ALS) but …

Amyotrophic lateral sclerosis (ALS) is characterized by selective and progressive
neurodegenerative changes in motor neural networks. Given the system complexity …

This study proposes a reliable computer-aided framework to identify gait fluctuations
associated with a wide range of degenerative neuromuscular disease (DNDs) and health …

How does the brain control movement? What sort of problems occur when the brain is sick?
Neurodegenerative disorders are illnesses that involve the death of certain parts of the …

Neurodegenerative disorders are a diversity of disorders, surrounding Alzheimer's (AD),
Parkinson's (PD), Huntington's diseases (HD), and amyotrophic lateral sclerosis (ALS) …

Amyotrophic lateral sclerosis (ALS) is a severe neurodegenerative disease, mainly affecting
the motor neurons (MNs) and without effective therapy. Drug screening is hampered by the …

The mammalian brain is a very complex organ containing an estimated 200 billion cells in
humans. Therefore, studying human brain development has become very challenging given …

Abstract Spinal Muscular Atrophy (SMA) is a neurodegenerative disease characterized by
specific and predominantly lower motor neuron (MN) loss. SMA is the main reason for infant …

Here we report a detailed investigation of the interaction of neuronal progenitor cells and
neurons with polyelectrolyte-stabilized magnetic iron oxide nanoparticles. Human neuronal …

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative primarily affecting
motor neurons, leading to disability and neuronal death, and ATP-Binding Cassette (ABC) …