[HTML][HTML] Prenatal maternal stress and offspring aggressive behavior: Intergenerational and transgenerational inheritance

NE Mbiydzenyuy, SMJ Hemmings… - Frontiers in behavioral …, 2022 - frontiersin.org
Even though studies have shown that prenatal maternal stress is associated with increased
reactivity of the HPA axis, the association between prenatal maternal stress and fetal …

Long non-coding RNAs: A double-edged sword in aging kidney and renal disease

YN Wang, CE Yang, DD Zhang, YY Chen, XY Yu… - Chemico-Biological …, 2021 - Elsevier
Aging as one of intrinsic biological processes is a risk factor for many chronic diseases.
Kidney disease is a global problem and health care burden worldwide. The diagnosis of …

Autonomous Pathway: FLOWERING LOCUS C Repression through an Antisense-Mediated Chromatin-Silencing Mechanism

Z Wu, X Fang, D Zhu, C Dean - Plant Physiology, 2020 - academic.oup.com
The timing of flowering is vital for plant reproductive success and is therefore tightly
regulated by endogenous and exogenous cues. In summer annual Arabidopsis …

[HTML][HTML] The conserved RNA-binding protein Seb1 promotes cotranscriptional ribosomal RNA processing by controlling RNA polymerase I progression

M Duval, C Yague-Sanz, TW Turowski… - Nature …, 2023 - nature.com
Transcription by RNA polymerase I (RNAPI) represents most of the transcriptional activity in
eukaryotic cells and is associated with the production of mature ribosomal RNA (rRNA). As …

An integrated model for termination of RNA polymerase III transcription

J Xie, U Aiello, Y Clement, N Haidara, M Girbig… - Science …, 2022 - science.org
RNA polymerase III (RNAPIII) synthesizes essential and abundant noncoding RNAs such as
transfer RNAs. Controlling RNAPIII span of activity by accurate and efficient termination is a …

Nutrient-dependent control of RNA polymerase II elongation rate regulates specific gene expression programs by alternative polyadenylation

C Yague-Sanz, Y Vanrobaeys… - Genes & …, 2020 - genesdev.cshlp.org
Transcription by RNA polymerase II (RNAPII) is a dynamic process with frequent variations
in the elongation rate. However, the physiological relevance of variations in RNAPII …

The conserved ribonuclease aCPSF1 triggers genome-wide transcription termination of Archaea via a 3′-end cleavage mode

L Yue, J Li, B Zhang, L Qi, Z Li, F Zhao, L Li… - Nucleic Acids …, 2020 - academic.oup.com
Transcription termination defines accurate transcript 3′-ends and ensures programmed
transcriptomes, making it critical to life. However, transcription termination mechanisms …

[PDF][PDF] CPF recruitment to non-canonical transcription termination sites triggers heterochromatin assembly and gene silencing

TV Vo, J Dhakshnamoorthy, M Larkin, M Zofall… - Cell reports, 2019 - cell.com
In eukaryotic genomes, heterochromatin is targeted by RNAi machinery and/or by pathways
requiring RNA elimination and transcription termination factors. However, a direct …

aCPSF1 cooperates with terminator U-tract to dictate archaeal transcription termination efficacy

J Li, L Yue, Z Li, W Zhang, B Zhang, F Zhao, X Dong - Elife, 2021 - elifesciences.org
Recently, aCPSF1 was reported to function as the long-sought global transcription
termination factor of archaea; however, the working mechanism remains elusive. This work …

[PDF][PDF] The chaperone FACT and histone H2B ubiquitination maintain S. pombe genome architecture through genic and subtelomeric functions

M Murawska, T Schauer, A Matsuda, MD Wilson… - Molecular cell, 2020 - cell.com
The histone chaperone FACT and histone H2B ubiquitination (H2Bub) facilitate RNA
polymerase II (Pol II) passage through chromatin, yet it is not clear how they cooperate …