[HTML][HTML] Prenatal maternal stress and offspring aggressive behavior: Intergenerational and transgenerational inheritance

NE Mbiydzenyuy, SMJ Hemmings… - Frontiers in behavioral …, 2022 - frontiersin.org
Even though studies have shown that prenatal maternal stress is associated with increased
reactivity of the HPA axis, the association between prenatal maternal stress and fetal …

[HTML][HTML] Transcriptional co-activators: emerging roles in signaling pathways and potential therapeutic targets for diseases

PD Talukdar, U Chatterji - Signal Transduction and Targeted Therapy, 2023 - nature.com
Specific cell states in metazoans are established by the symphony of gene expression
programs that necessitate intricate synergic interactions between transcription factors and …

Autonomous Pathway: FLOWERING LOCUS C Repression through an Antisense-Mediated Chromatin-Silencing Mechanism

Z Wu, X Fang, D Zhu, C Dean - Plant Physiology, 2020 - academic.oup.com
The timing of flowering is vital for plant reproductive success and is therefore tightly
regulated by endogenous and exogenous cues. In summer annual Arabidopsis …

An integrated model for termination of RNA polymerase III transcription

J Xie, U Aiello, Y Clement, N Haidara, M Girbig… - Science …, 2022 - science.org
RNA polymerase III (RNAPIII) synthesizes essential and abundant noncoding RNAs such as
transfer RNAs. Controlling RNAPIII span of activity by accurate and efficient termination is a …

The conserved ribonuclease aCPSF1 triggers genome-wide transcription termination of Archaea via a 3′-end cleavage mode

L Yue, J Li, B Zhang, L Qi, Z Li, F Zhao, L Li… - Nucleic Acids …, 2020 - academic.oup.com
Transcription termination defines accurate transcript 3′-ends and ensures programmed
transcriptomes, making it critical to life. However, transcription termination mechanisms …

[HTML][HTML] The conserved RNA-binding protein Seb1 promotes cotranscriptional ribosomal RNA processing by controlling RNA polymerase I progression

M Duval, C Yague-Sanz, TW Turowski… - Nature …, 2023 - nature.com
Transcription by RNA polymerase I (RNAPI) represents most of the transcriptional activity in
eukaryotic cells and is associated with the production of mature ribosomal RNA (rRNA). As …

Nutrient-dependent control of RNA polymerase II elongation rate regulates specific gene expression programs by alternative polyadenylation

C Yague-Sanz, Y Vanrobaeys… - Genes & …, 2020 - genesdev.cshlp.org
Transcription by RNA polymerase II (RNAPII) is a dynamic process with frequent variations
in the elongation rate. However, the physiological relevance of variations in RNAPII …

[HTML][HTML] CPF recruitment to non-canonical transcription termination sites triggers heterochromatin assembly and gene silencing

TV Vo, J Dhakshnamoorthy, M Larkin, M Zofall… - Cell reports, 2019 - cell.com
In eukaryotic genomes, heterochromatin is targeted by RNAi machinery and/or by pathways
requiring RNA elimination and transcription termination factors. However, a direct …

[HTML][HTML] The chaperone FACT and histone H2B ubiquitination maintain S. pombe genome architecture through genic and subtelomeric functions

M Murawska, T Schauer, A Matsuda, MD Wilson… - Molecular cell, 2020 - cell.com
The histone chaperone FACT and histone H2B ubiquitination (H2Bub) facilitate RNA
polymerase II (Pol II) passage through chromatin, yet it is not clear how they cooperate …

Senataxin homologue Sen1 is required for efficient termination of RNA polymerase III transcription

J Rivosecchi, M Larochelle, C Teste, F Grenier… - The EMBO …, 2019 - embopress.org
R‐loop disassembly by the human helicase Senataxin contributes to genome integrity and
to proper transcription termination at a subset of RNA polymerase II genes. Whether …